{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:15:55Z","timestamp":1747185355993,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>It is unknown whether 5\u2010year overall survival (OS) differs and to what extent between the American Joint Committee on Cancer stage III non\u2010seminoma testicular germ cell tumor (NS\u2010TGCT) patients and simulated age\u2010matched male population\u2010based controls, according to race\/ethnicity groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified newly diagnosed (2004\u20132014) stage III NS\u2010TGCT patients within the Surveillance Epidemiology and End Results database 2004\u20132019. For each case, we simulated an age\u2010matched male control (Monte Carlo simulation), relying on Social Security Administration (SSA) Life Tables with 5\u2009years of follow\u2010up. We compared OS rates between stage III NS\u2010TGCT patients and simulated age\u2010matched male population\u2010based controls, according to race\/ethnicity groups (Caucasian, Hispanic, Asian\/Pacific Islander and African American). Both, cancer\u2010specific mortality (CSM) and other\u2010cause mortality (OCM) were computed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 2054 stage III NS\u2010TGCT patients, 60% were Caucasians versus 33% Hispanics versus 4% Asians\/Pacific Islanders versus 3% African Americans. The 5\u2010year OS difference between stage III NS\u2010TGCT patients versus simulated age\u2010matched male population\u2010based controls was highest in Asians\/Pacific Islanders (64 vs. 99%, \u0394\u2009=\u200935%), followed by African Americans (66 vs. 97%, \u0394\u2009=\u200931%), Hispanics (72 vs. 99%, \u0394\u2009=\u200927%), and Caucasians (76 vs. 98%, \u0394\u2009=\u200922%). The 5\u2010year CSM rate was highest in Asians\/Pacific Islanders (32%), followed by African Americans (26%), Hispanics (25%), and Caucasians (20%). The 5\u2010year OCM rate was highest in African Americans (8%), followed by Caucasians (4%), Asians\/Pacific Islanders (4%), and Hispanics (2%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Relative to SSA Life Tables, the highest 5\u2010year OS disadvantage applied to stage III NS\u2010TGCT Asian\/Pacific Islander race\/ethnicity group, followed by African American, Hispanic and Caucasian, in that order.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15532","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T01:15:45Z","timestamp":1720228545000},"page":"1137-1143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Survival of stage <scp>III<\/scp> non\u2010seminoma testis cancer patients versus simulated controls, according to race\/ethnicity"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5340-8569","authenticated-orcid":false,"given":"Simone","family":"Morra","sequence":"first","affiliation":[{"name":"Division of Urology, Cancer Prognostics and Health Outcomes Unit University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Neurosciences, Science of Reproduction and Odontostomatology University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4829-0241","authenticated-orcid":false,"given":"Cristina","family":"Cano Garcia","sequence":"additional","affiliation":[{"name":"Division of Urology, Cancer Prognostics and Health Outcomes Unit University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology University Hospital Frankfurt, Goethe University Frankfurt am Main  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattia Luca","family":"Piccinelli","sequence":"additional","affiliation":[{"name":"Division of Urology, Cancer Prognostics and Health Outcomes Unit University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology IEO European Institute of Oncology, IRCCS  Milan Italy"},{"name":"Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9712-2685","authenticated-orcid":false,"given":"Stefano","family":"Tappero","sequence":"additional","affiliation":[{"name":"Division of Urology, Cancer Prognostics and Health Outcomes Unit University of Montr\u00e9al Health Center  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Urology IRCCS Policlinico San Martino  Genoa Italy"},{"name":"Department of Surgical and Diagnostic Integrated Sciences (DISC) University of Genova  Genoa 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