{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T22:23:07Z","timestamp":1780093387207,"version":"3.54.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T00:00:00Z","timestamp":1736640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the efficacy of staged urethroplasty for complex anterior urethral strictures from both surgical and patient\u2010reported outcome perspectives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 100 patients who underwent staged urethroplasty for anterior urethral strictures between May 2011 and June 2023. Anatomical success was defined as the ability to pass cystourethroscopy without resistance and the patient's ability to void without additional interventions. Patient\u2010reported outcomes were evaluated using validated questionnaires, including the urethral stricture surgery patient\u2010reported outcome measure, sexual health inventory for men (SHIM), and EuroQol 5\u2010dimension (EQ\u20105D), administered pre\u2010and postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At a median follow\u2010up of 53\u2009months, the anatomical success rate was 89.0%. Seventeen (17.0%) required revision surgery between stages. Perioperative complications occurred in 13 (13.0%). Significant improvements were observed in maximum flow rate (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), postvoid residual volume (<jats:italic>p<\/jats:italic>\u2009=\u20090.0006), total lower urinary tract symptoms (LUTS) scores (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), LUTS\u2010specific quality of life (QOL) score (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), EQ\u20105D index score (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), and EQ\u20105D visual analog scale score (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). SHIM scores showed no significant change (<jats:italic>p<\/jats:italic>\u2009=\u20090.59). Overall, 93.5% of patients reported being either \u201csatisfied\u201d or \u201cvery satisfied\u201d with the outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Staged urethroplasty demonstrates high anatomical success rates and significant improvements in urinary function and QOL without compromising erectile function. The high patient satisfaction rate supports its efficacy in treating complex anterior urethral strictures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.15679","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T07:20:22Z","timestamp":1736752822000},"page":"441-446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Surgical and patient\u2010reported outcomes of staged urethroplasty for anterior urethral strictures: A comprehensive analysis"],"prefix":"10.1111","volume":"32","author":[{"given":"Takahiro","family":"Minami","sequence":"first","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7678-6375","authenticated-orcid":false,"given":"Akio","family":"Horiguchi","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"},{"name":"Division of Trauma and Reconstruction National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5860-6318","authenticated-orcid":false,"given":"Masayuki","family":"Shinchi","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Ojima","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhei","family":"Segawa","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Takekawa","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadayoshi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakaru","family":"Masumoto","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jumpei","family":"Katsuta","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Therapeutics Juntendo University Graduate School of Medicine  Bunkyo\u2010ku Japan"},{"name":"Department of Urology Koto Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Urology National Defense Medical College  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.15512"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.5895"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-021-03676-8"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13356"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.03.081"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.10.020"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.10.013"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11236961"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(95)90023-3"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10842.x"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.02.010"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000069721.20193.fd"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2016.08.001"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2011.01.042"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.40618"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2540-z"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.2990150507"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8510(90)90421-9"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-019-0466-4"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.04.055"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.15679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T05:38:12Z","timestamp":1744004292000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.15679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,12]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/iju.15679"],"URL":"https:\/\/doi.org\/10.1111\/iju.15679","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,12]]},"assertion":[{"value":"2024-09-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}