{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T17:18:53Z","timestamp":1778951933741,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To identify risk factors of infectious complications following mini\u2010endoscopic combined intrarenal surgery (ECIRS) in patients with renal or ureteral stones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed consecutive patients with renal or ureteral stones who underwent mini\u2010ECIRSs at three Japanese tertiary institutions between 2015 and 2021. Data were collected and evaluated regarding patient backgrounds, stone characteristics, and postoperative complications. Among the various complications, multivariable logistic regression analysis was performed using preoperative and intraoperative factors for postoperative fever (\u2265\u200938\u00b0C) and septic shock to identify independent risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The data of 1432 cases were collected. Finally, 1035 cases of single\u2010session mini\u2010ECIRS were included in the analysis. In infectious complications, postoperative fever and septic shock were observed in 273 and 21 patients (26.4% and 2.0%). A multivariable logistic regression model identified female (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), ureteral stones (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), preoperative pyuria (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), preoperative urinary tract infection (<jats:italic>p<\/jats:italic>\u2009=\u20090.045), preoperative percutaneous nephrostomy (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), and operation time (<jats:italic>p<\/jats:italic>\u2009=\u20090.017) as predictors of postoperative fever. For septic shock, female (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) was shown as a risk factor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To the best of our knowledge, this multicenter cohort study is the largest study investigating infectious complications following mini\u2010ECIRS. Female was a common risk factor for both postoperative fever and septic shock, suggesting that surgeons should pay extra attention to vital signs during the procedure and postoperative infectious complications in mini\u2010ECIRSs for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iju.70037","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T09:41:21Z","timestamp":1741772481000},"page":"703-709","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Infectious Complications Following Mini\u2010Endoscopic Combined Intrarenal Surgery at Japanese Tertiary Institutions"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8815-9458","authenticated-orcid":false,"given":"Takahiko","family":"Watanabe","sequence":"first","affiliation":[{"name":"Department of Urology Yokosuka Kyosai Hospital  Yokosuka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4433-370X","authenticated-orcid":false,"given":"Hiroki","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Urology Yokosuka Kyosai Hospital  Yokosuka Japan"},{"name":"Department of Urology Yokohama City University Graduate School of Medicine  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Urology Ohguchi East General Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2162-7756","authenticated-orcid":false,"given":"Fukashi","family":"Yamamichi","sequence":"additional","affiliation":[{"name":"Department of Urology Hara Genitourinary Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1416-4877","authenticated-orcid":false,"given":"Tadashi","family":"Tabei","sequence":"additional","affiliation":[{"name":"Department of Urology Yokosuka Kyosai Hospital  Yokosuka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8818-952X","authenticated-orcid":false,"given":"Takaaki","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Urology Hara Genitourinary Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3950-1358","authenticated-orcid":false,"given":"Junichi","family":"Matsuzaki","sequence":"additional","affiliation":[{"name":"Department of Urology Ohguchi East General Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Urology Yokosuka Kyosai Hospital  Yokosuka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.07.073"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-017-1015-9"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-011-0790-0"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.08.026"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.07.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2016.05.038"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13124"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2013.0361"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2016.02.056"},{"key":"e_1_2_10_11_1","article-title":"The Safety and Efficacy of Endoscopic Combined Intrarenal Surgery Versus Percutaneous Nephrolithotomy: A Systematic Review and Meta\u2010Analysis","volume":"11","author":"Victor A.","year":"2022","journal-title":"Advances in Urology"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-020-02433-x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57090872"},{"key":"e_1_2_10_14_1","first-page":"437","article-title":"Risk Factors for Infectious Complications After Retrograde Intrarenal Surgery\u2014A Systematic Review and Narrative Synthesis","volume":"74","author":"Dybowski B.","year":"2021","journal-title":"Central European Journal of Urology"},{"key":"e_1_2_10_15_1","first-page":"17","article-title":"The Influencing Factors of Infectious Complications After Percutaneous Nephrolithotomy: A Systematic Review and Meta\u2010Analysis","volume":"51","author":"Guiming Z.","year":"2023","journal-title":"Urolithiasis"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.15363"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345\u2010012\u20100836\u2010y"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000336164"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/21681805.2017.1284897"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2022.0579"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345\u2010012\u20101002\u20102"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2022.0544"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.70037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T03:03:21Z","timestamp":1749438201000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.70037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,4]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/iju.70037"],"URL":"https:\/\/doi.org\/10.1111\/iju.70037","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,4]]},"assertion":[{"value":"2024-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}