{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:53:17Z","timestamp":1787014397063,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the prevalence, impact on health\u2010related quality of life (HRQOL), and predictive factors of co\u2010existent overactive\u2010underactive bladder (COUB) in women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>3088 Japanese women aged \u2265\u200920\u2009years responding to a nationwide internet survey on lower urinary tract symptoms (LUTS) were included. Participants were divided into COUB, overactive bladder (OAB) alone, underactive bladder (UAB) alone, and non\u2010OAB\/UAB groups based on the OAB symptom score and the International Continence Society\u2010Working Group definition of UAB. In addition to the prevalence, we assessed each group's HRQOL and physician visit rates. We further explored predictors of COUB as well as OAB and UAB using multinomial logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalences of COUB, OAB alone, and UAB alone were 1.6%, 8.2%, and 2.4%, respectively, and all increased significantly with age. The proportions of COUB in OAB and UAB overall were 16.4% and 40.7%, respectively. The proportions of participants who responded that their HRQOL was affected and those visiting physicians were both highest in the COUB group. Multinomial logistic regression analysis showed that age, frailty, neurological disorders, anorectal dysfunction, pelvic organ prolapse, and parity (\u2265\u20093) were independent predictors for COUB, of which age, neurological disorders, and parity were exclusively associated with COUB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although not highly prevalent, COUB may have a significant impact on adult women, especially frail and multimorbid elderly women. More attention should be paid to this unique condition for optimal LUTS management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iju.70120","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T06:25:45Z","timestamp":1747981545000},"page":"1186-1194","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence, Impact on Quality of Life, and Predictive Factors of Co\u2010Existent Overactive\u2010Underactive Bladder in Women"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0169-4783","authenticated-orcid":false,"given":"Noritoshi","family":"Sekido","sequence":"first","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Urology Toho University Ohashi Medical Center  Meguro Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Omae","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Innovative Research and Education for Clinicians and Trainees (DiRECT) Fukushima Medical University Hospital  Fukushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3618-5214","authenticated-orcid":false,"given":"Nobuhiro","family":"Haga","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Urology, Faculty of Medicine Fukuoka University  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasue","family":"Kubota","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Advanced Medical Nursing Nagoya City University Graduate School of Nursing  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2962-1607","authenticated-orcid":false,"given":"Motoaki","family":"Saito","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Pharmacology, Kochi Medical School Kochi University  Nankoku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuji","family":"Sakakibara","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Neurology Clinic Tsudanuma and Dowakai Chiba Hospital  Funabashi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikako","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Women's Health Nursing &amp; Midwifery Tohoku University Graduate School of Medicine  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0408-3678","authenticated-orcid":false,"given":"Takahiko","family":"Mitsui","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Urology University of Yamanashi Graduate School of Medical Sciences  Chuo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6324-0739","authenticated-orcid":false,"given":"Naoya","family":"Masumori","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Urology Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0819-9478","authenticated-orcid":false,"given":"Satoru","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Epidemiological Survey Executive Committee The Japanese Continence Society  Chiyoda Japan"},{"name":"Department of Urology Nihon University School of Medicine  Itabashi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07601.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08371.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23701"},{"issue":"3","key":"e_1_2_11_5_1","first-page":"S50","article-title":"Is Coexistent Overactive\u2010Underactive Bladder (With or Without Detrusor Overactivity and Underactivity) a Real Clinical Syndrome? 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