{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:56:55Z","timestamp":1773017815047,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n Transperineal prostate biopsy (TP\u2010Bx) is increasingly preferred due to its lower infection risk and improved clinically significant prostate cancer detection rates. Its feasibility under local anesthesia provides both clinical and economic advantages. However, acute urinary retention (AUR) remains a significant post\u2010procedure concern. This study aims to evaluate the impact of transperineal prostate biopsy performed under local anesthesia on voiding function using uroflowmetry parameters.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n A prospective observational study was conducted with 74 patients. TP\u2010Bx was performed under local anesthesia using a freehand technique. Uroflowmetry parameters, including maximum urinary flow rate (\n Q<\/jats:italic>\n max<\/jats:sub>\n , mL\/s), average urinary flow rate (\n Q<\/jats:italic>\n ave<\/jats:sub>\n , mL\/s), voided volume (\n V<\/jats:italic>\n v<\/jats:sub>\n , mL), and post\u2010void residual volume (PVR), were assessed before and after the procedure to evaluate its impact on voiding function.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The average changes in\n Q<\/jats:italic>\n max<\/jats:sub>\n and\n Q<\/jats:italic>\n ave<\/jats:sub>\n between pre and post procedure were 1.78\u2009\u00b1\u20094.33 and 0.63\u2009\u00b1\u20091.70, respectively. A significant reduction in\n Q<\/jats:italic>\n max<\/jats:sub>\n and\n Q<\/jats:italic>\n ave<\/jats:sub>\n was observed after TP\u2010Bx (\n p<\/jats:italic>\n \u2009<\u20090.001). PVR increased after TP\u2010Bx (\n p<\/jats:italic>\n \u2009<\u20090.001); however, these changes were mild and did not require catheterization.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n With increasing experience, TP\u2010Bx has become safer. The use of local anesthesia reduces anesthesia\u2010related complications, and the historically feared risk of AUR appears lower than previously assumed. These findings support TP\u2010Bx as a safe and effective diagnostic approach.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/iju.70377","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T06:01:31Z","timestamp":1770703291000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Local Anesthetic Transperineal Prostate Biopsy: Does It Affect Uroflowmetry Results"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2786-0716","authenticated-orcid":false,"given":"\u0130sa","family":"Da\u011fl\u0131","sequence":"first","affiliation":[{"name":"Department of Urology University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6954-709X","authenticated-orcid":false,"given":"Muhammed Z\u00fcbeyr","family":"Canbolat","sequence":"additional","affiliation":[{"name":"Department of Urology University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9679-548X","authenticated-orcid":false,"given":"Tuncel","family":"Uzel","sequence":"additional","affiliation":[{"name":"Department of Urology University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8157-6314","authenticated-orcid":false,"given":"Abdullah","family":"\u00c7ay\u0131rl\u0131","sequence":"additional","affiliation":[{"name":"Department of Urology University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0366-9055","authenticated-orcid":false,"given":"Mehmet","family":"Duvarc\u0131","sequence":"additional","affiliation":[{"name":"Department of Urology University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2360-788X","authenticated-orcid":false,"given":"Erdem","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Urology University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2023.05.036"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2023.08.001"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2012.01.001"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.17593"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2024.11.064"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2023.05.020"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41669-021-00277-4"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000002043.16"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.08.004"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2390-8"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.01.045"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12415"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.15056"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2024.01.019"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391\u2010024\u201000934\u20109"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.02.008"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15039"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31819f7aea"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2009.07.010"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-019-1573-0"},{"issue":"12","key":"e_1_2_12_22_1","article-title":"Comparing the Efficacy and Safety of the Transperineal Versus Transrectal Prostate Biopsy Approach in the Diagnosis of Prostate Cancer: A Systematic Review and Meta\u2010Analysis","volume":"16","author":"Abdulrasheed H.","year":"2024","journal-title":"Cureus"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2024.07.009"}],"container-title":["International Journal of Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.70377","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iju.70377","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iju.70377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:57:49Z","timestamp":1773014269000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iju.70377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/iju.70377"],"URL":"https:\/\/doi.org\/10.1111\/iju.70377","archive":["Portico"],"relation":{},"ISSN":["0919-8172","1442-2042"],"issn-type":[{"value":"0919-8172","type":"print"},{"value":"1442-2042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-10-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70377"}}