{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T09:55:49Z","timestamp":1781862949058,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to investigate age at surgery for cryptorchidism and to identify factors associated with early surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study investigated 664 cases of cryptorchidism treated surgically between 2007 and 2023. Early surgery was defined as surgery at less than 1\u2009year old. The cases detected at birth or at the 1\u2010month checkup were defined as early detected cases and age at initial visit less than 6\u2009months old was defined as early initial visit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The proportion of early surgery increased over time, from 6.3% in 2007\u20132011 to 30.9% in 2020\u20132023 (OR 1.67, 95% CI 1.39\u20132.02;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Multivariate analyses demonstrated that early initial visit, era of surgery, hypospadias and multiple congenital anomalies were independently associated with early surgery. Among 200 early detected cases, 55.5% of these had delayed initial visits (at or over 6\u2009months old). In early detected cases, multivariate analysis demonstrated that the shorter intervals from detection to initial visit and from surgical plan to the date of surgery were independently associated with early surgery. Even among early detected and early visiting cases, some surgeries were delayed due to patient\u2010related factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Age at initial visit is getting earlier, and surgery for cases less than 1\u2009year old is also increasing, but remains insufficient. To achieve earlier surgical intervention for cryptorchidism, an early initial visit is essential. When findings suggestive of cryptorchidism are identified, immediate referral is crucial, and further observation is unnecessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iju.70475","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:21:59Z","timestamp":1777468919000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of the Trend in Timing of Surgery for Cryptorchidism: Has Earlier Surgical Intervention Been Achieved"],"prefix":"10.1111","volume":"33","author":[{"given":"Taiju","family":"Hyuga","sequence":"first","affiliation":[{"name":"Department of Pediatric Urology Jichi Medical University, Children's Medical Center Tochigi  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Sugimura","sequence":"additional","affiliation":[{"name":"Department of Pediatric Urology Jichi Medical University, Children's Medical Center Tochigi  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Muto","sequence":"additional","affiliation":[{"name":"Department of Pediatric Urology Jichi Medical University, Children's Medical Center Tochigi  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimihiko","family":"Moriya","sequence":"additional","affiliation":[{"name":"Department of Pediatric Urology Jichi Medical University, Children's Medical Center Tochigi  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"376","article-title":"Improved Sperm Count and Motility in Young Men Surgically Treated for Cryptorchidism in the First Year of Life","volume":"24","author":"Feyles F.","year":"2014","journal-title":"European Journal of Pediatric 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