{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:47:33Z","timestamp":1791568053364,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Urology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Lower urinary tract symptoms (LUTS) are common in men and have been linked to mental health, but their relationship with depressive symptoms across the adult age range, including young men, remains unclear. We examined the association between LUTS and depressive symptoms in Japanese men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using an internet research panel, 4000 never\u2010smoking Japanese men were surveyed. LUTS were assessed with the Overactive Bladder Symptom Score (OABSS), International Consultation on Incontinence Questionnaire\u2010Short Form (ICIQ\u2010SF), International Prostate Symptom Score (IPSS), and Quality of Life (QOL) index, and depressive symptoms with the Quick Inventory of Depressive Symptomatology, Japanese version (QIDS\u2010J). Scores were compared across QIDS\u2010J severity groups, and multivariable regression was used to adjust for age and household income.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 2568 respondents (mean age 46.6\u2009years), more severe depressive symptoms were associated with younger age (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). ICIQ\u2010SF and IPSS increased with QIDS\u2010J severity (both\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and remained independently associated after adjustment for age and income (IPSS adjusted\n                      <jats:italic>\u03b2<\/jats:italic>\n                      0.32; ICIQ\u2010SF 0.13; both\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), whereas OABSS was not associated (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.193). The same pattern was observed in men aged 20\u201340\u2009years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Greater depressive symptom severity was independently associated with higher IPSS and ICIQ\u2010SF scores, but not with OABSS, OAB, or UUI among Japanese male never\u2010smokers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iju.70655","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:54:47Z","timestamp":1790776487000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Depressive Symptom Severity Is Associated With\n                    <scp>IPSS<\/scp>\n                    and\n                    <scp>ICIQ<\/scp>\n                    \u2010\n                    <scp>SF<\/scp>\n                    Scores but Not Overactive Bladder in Japanese Male Never\u2010Smokers"],"prefix":"10.1111","volume":"33","author":[{"given":"Masanobu","family":"Yamazaki","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahoko","family":"Ninomiya","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1054-0779","authenticated-orcid":false,"given":"Akihito","family":"Hashizume","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-5487","authenticated-orcid":false,"given":"Teppei","family":"Takeshima","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4433-370X","authenticated-orcid":false,"given":"Hiroki","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Urology Yokohama City University, Graduate School of Medicine  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7449-2015","authenticated-orcid":false,"given":"Kazuhide","family":"Makiyama","sequence":"additional","affiliation":[{"name":"Department of Urology Yokohama City University, Graduate School of Medicine  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroji","family":"Uemura","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1499-546X","authenticated-orcid":false,"given":"Jun\u2010Ichi","family":"Teranishi","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7049-3379","authenticated-orcid":false,"given":"Takashi","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation Yokohama City University Medical Center  Yokohama Japan"},{"name":"Department of Urology Yokohama City University, Graduate School of Medicine  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"issue":"3","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1464-410X.2009.08369.x","article-title":"The Overlap of Storage, Voiding and Postmicturition Symptoms and Implications for Treatment Seeking in the USA, UK and Sweden: EpiLUTS","volume":"103","author":"Sexton C. 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