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By participating in the Sensory Science Exhibition, held at St Catharine's College, University of Cambridge as part of the Cambridge Festival, we sought to address this problem by creating a 3D mammalian cell with model bacteria, including <jats:italic>Salmonella enterica<\/jats:italic>, <jats:italic>Chlamydia trachomatis<\/jats:italic> and <jats:italic>Orientia tsutsugamushi.<\/jats:italic> By hijacking eukaryotic host cellular machinery and avoiding detection, these bacteria orchestrate their survival and replication within host cells. This tactile display aimed to guide participants through key aspects of intracellular bacterial life cycles such as host cell entry, <jats:italic>Salmonella<\/jats:italic> type three secretion system (T3SS) protein secretion, <jats:italic>O.\u2009tsutsugamushi<\/jats:italic> trafficking along microtubules, and <jats:italic>C.\u2009trachomatis<\/jats:italic> replication within an inclusion. We summarize our experiences in this report. We hope our multisensory conceptualization of intracellular bacteria provided inclusive and easy\u2010to\u2010understand communication of complex science concepts to the general public with modalities also accessible to the low\u2010vision and blind communities.<\/jats:p>","DOI":"10.1111\/imcb.70019","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T20:25:03Z","timestamp":1745439903000},"page":"535-540","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Touching the invisible: exploring intracellular host\u2013pathogen interactions through multisensory art"],"prefix":"10.1111","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9773-354X","authenticated-orcid":false,"given":"Rachel Elizabeth","family":"Jackson","sequence":"first","affiliation":[{"name":"Cambridge Institute for Medical Research University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Biochemistry University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Weild","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Atlavina","sequence":"additional","affiliation":[{"name":"Cambridge School of Art Anglia Ruskin University  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Aylward","sequence":"additional","affiliation":[{"name":"Cambridge Institute for Medical Research University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Harris","sequence":"additional","affiliation":[{"name":"Cambridge Institute for Medical Research University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Hayward","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla","family":"Godlee","sequence":"additional","affiliation":[{"name":"Department of Biochemistry University of Cambridge  Cambridge UK"},{"name":"Department of Pathology University of Cambridge  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/imcb.12738"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/imcb.12759"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/imcb.12760"},{"key":"e_1_2_12_5_1","first-page":"27","article-title":"Sensory science","volume":"46","author":"Liston A","year":"2024","journal-title":"Biochem J"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/650733"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12561"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.001292"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.07.009"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11051283"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a010256"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01745-0"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2022.101888"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.1.494-500.2001"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31176-9"},{"key":"e_1_2_12_16_1","unstructured":"DeesJ.The aromatic world of microbes: exploring the delightful and repulsive smells.2023.Joyful Microbe.https:\/\/joyfulmicrobe.com\/microbial\u2010smells\/. 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