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Anticoagulation in systemic sclerosis\u2010related<jats:styled-content style=\"fixed-case\">PAH<\/jats:styled-content>(<jats:styled-content style=\"fixed-case\">SSc<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PAH<\/jats:styled-content>) is currently one of the most contentious issues in the management of patients with connective tissue disease. While some studies have shown a survival benefit with warfarin therapy in this disease, others have not. Accordingly, a state of clinical equipoise exists in relation to anticoagulation in<jats:styled-content style=\"fixed-case\">SSc<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PAH<\/jats:styled-content>. 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