{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:35:52Z","timestamp":1791171352505,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T00:00:00Z","timestamp":1392595200000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100014743","name":"Arrow Bone Marrow Transplant Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014743","id-type":"DOI","asserted-by":"crossref"}]},{"name":"St Vincent's Haematology Research Funds"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2014,2]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Survival after allogeneic haemopoietic stem cell transplantation (allo\u2010HSCT<\/jats:styled-content>) has improved because of advancements in allo\u2010HSCT<\/jats:styled-content>. Allo\u2010HSCT<\/jats:styled-content> has been performed in A<\/jats:styled-content>ustralia since the late 1970s. However, there are few published data about health problems of allo\u2010HSCT<\/jats:styled-content> survivors in A<\/jats:styled-content>ustralia.<\/jats:p><\/jats:sec>Aims<\/jats:title>Identify health issues in long\u2010term survivors of allo\u2010HSCT<\/jats:styled-content> in an A<\/jats:styled-content>ustralian centre to manage better and prevent long\u2010term complications.<\/jats:p><\/jats:sec>Methods<\/jats:title>The health records of all patients of allo\u2010HSCT<\/jats:styled-content> in a single centre from J<\/jats:styled-content>anuary 2000 to D<\/jats:styled-content>ecember 2007 and survived beyond 2 years were assessed.<\/jats:p><\/jats:sec>Results<\/jats:title>Ninety\u2010nine of the 200 allo\u2010HSCT<\/jats:styled-content> patients survived beyond 2 years, and the median time from allo\u2010HSCT<\/jats:styled-content> was 74 months. Twenty\u2010eight\u2009per\u2009cent died at a median of 37 months after allo\u2010HSCT<\/jats:styled-content> because of relapsed malignancy (12%), stroke (1%), infection (3%), chronic graft versus host disease (9%), secondary malignancy (2%) and unknown cause (1%). Ninety\u2010one\u2009per\u2009cent reported one or more chronic health conditions. Health issues were chronic graft versus host disease (70%); respiratory (66%), ophthalmic (40%), bone (33%), and renal (26%) problems; and malignancies (14% skin, 3% solid organ). Seventy\u2010nine\u2009per\u2009cent resumed vocation at full or reduced capacity 2 years after allo\u2010HSCT<\/jats:styled-content>. Clinicians identified 40% with quality of life (QOL<\/jats:styled-content>) issues, but survivors\u2019 self\u2010reported QOL<\/jats:styled-content> was comparable with the general A<\/jats:styled-content>ustralian population.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This study shows that allo\u2010HSCT<\/jats:styled-content> patients are living with high burdens of chronic diseases that warrant lifelong surveillance and engagement with healthcare. Structured, multi\u2010disciplinary care as recommended by published guidelines for allo\u2010HSCT<\/jats:styled-content> survivors may reduce long\u2010term effects and improve their outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.12336","type":"journal-article","created":{"date-parts":[[2013,12,10]],"date-time":"2013-12-10T06:58:44Z","timestamp":1386658724000},"page":"139-147","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Health status, late effects and long\u2010term survivorship of allogeneic bone marrow transplantation: a retrospective study"],"prefix":"10.1111","volume":"44","author":[{"given":"G.","family":"Gifford","sequence":"first","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplantation St Vincent's Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Sim","sequence":"additional","affiliation":[{"name":"Department of Haematology Princess Margaret Hospital Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Horne","sequence":"additional","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplantation St Vincent's Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplantation St Vincent's Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2010.02262.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.06.014"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.6693"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-10-263095"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2008.1.125"},{"key":"e_1_2_7_7_1","first-page":"236","volume-title":"EBMT (European Group for Bone Marrow Transplantation) Handbook","author":"Tichelli A","year":"2008"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2010.1.229"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2005.09.012"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2012.5"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-06-229369"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-348730"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.19.2335"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1428"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.33.7212"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.189"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700806"},{"key":"e_1_2_7_18_1","unstructured":"BourchierM.Cardiovascular Disease Australian Facts 2011. 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