{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T12:46:01Z","timestamp":1776689161054,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Waikato District Health Board","award":["-"],"award-info":[{"award-number":["-"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To date no incidence figures for upper gastrointestinal haemorrhage (UGIH) in New Zealand have been published.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the incidence of <jats:styled-content style=\"fixed-case\">UGIH<\/jats:styled-content> in a demographically defined population, and to assess variation in incidence associated with demographic parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 17 March 2001 and 12 October 2010, all patients presenting to <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>aikato <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital with <jats:styled-content style=\"fixed-case\">UGIH<\/jats:styled-content> were prospectively ascertained, and clinical, epidemiological and laboratory data were collected. Incidence rates were calculated, and were age adjusted to the World Health Organization world standard population. Parameters associated with trends in incidence were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 1360 <jats:styled-content style=\"fixed-case\">UGIH<\/jats:styled-content> events, yielding a crude incidence of 59.2 per 100\u2009000 adults (age \u2265 15 years) per year (all quoted incidence figures per 100\u2009000 adults per year), and an age\u2010adjusted incidence (<jats:styled-content style=\"fixed-case\">AAI<\/jats:styled-content>) of 46.4. <jats:styled-content style=\"fixed-case\">AAI<\/jats:styled-content> was higher for <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aori compared with <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand Europeans (91.3 vs 37.0, rate ratio (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>) = 2.47, <jats:italic>P<\/jats:italic> &lt; 0.001). <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aori were more likely to have a gastric ulcer at endoscopy (odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) = 2.21, <jats:italic>P<\/jats:italic> &lt; 0.001). For those tested for <jats:styled-content style=\"fixed-case\"><jats:italic>H<\/jats:italic><\/jats:styled-content><jats:italic>elicobacter pylori<\/jats:italic> (<jats:italic>n<\/jats:italic> = 702), <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aori were more likely to be infected (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 2.12, <jats:italic>P<\/jats:italic> &lt; 0.001). <jats:styled-content style=\"fixed-case\">AAI<\/jats:styled-content> was higher for males (61.1 vs 33.6, <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> = 1.82, <jats:italic>P<\/jats:italic> &lt; 0.001). Males were more likely to have a duodenal ulcer at endoscopy (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> = 1.79, <jats:italic>P<\/jats:italic> &lt; 0.001). <jats:styled-content style=\"fixed-case\">AAI<\/jats:styled-content> incidence decreased from the first to the second half of the study period (53.6 vs 45.8, <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> = 1.17, <jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AAI<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">UGIH<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>aikato region was 46.4. This was significantly higher in <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aori and in males, and decreased over the study period. These data will provide a comparison for future assessment of trends in <jats:styled-content style=\"fixed-case\">UGIH<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.12489","type":"journal-article","created":{"date-parts":[[2014,6,3]],"date-time":"2014-06-03T13:52:39Z","timestamp":1401803559000},"page":"735-741","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Incidence of upper gastrointestinal haemorrhage in <scp>M<\/scp>aori and <scp>N<\/scp>ew <scp>Z<\/scp>ealand <scp>E<\/scp>uropean ethnic groups, 2001\u20132010"],"prefix":"10.1111","volume":"44","author":[{"given":"J.","family":"Irwin","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Waikato Hospital  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Ferguson","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Weilert","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Waikato Hospital  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Waikato Hospital  Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01865.x"},{"key":"e_1_2_7_3_1","first-page":"568","article-title":"Analysis of 3294 cases of upper gastrointestinal bleeding in military medical facilities","volume":"90","author":"Yavorski RT","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07517.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.6999.222"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.06037.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7107.510"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32834c3a02"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2012.763174"},{"key":"e_1_2_7_10_1","unstructured":"Statistics New Zealand.Home \u2013 statistics New Zealand: 2001 and 2006 census data [Internet]. 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