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As a result of elevated pressures within the portal vein several complications can arise, including the development of oesophageal and gastric varices, ascites, hepatic encephalopathy as well as complications secondary to circulatory dysfunction, such as hepatorenal syndrome, portopulmonary syndrome and hepatopulmonary syndrome. This review outlines the pathogenesis and diagnosis of portal hypertension and outlines the management of these various important clinical sequelae. The management of oesophageal and gastric varices is particularly important, and both the emergency management together with prophylactic management of this condition are described.<\/jats:p>","DOI":"10.1111\/imj.12590","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T12:36:57Z","timestamp":1410957417000},"page":"16-26","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":98,"title":["Portal hypertension: pathophysiology, diagnosis and management"],"prefix":"10.1111","volume":"45","author":[{"given":"S.","family":"Bloom","sequence":"first","affiliation":[{"name":"Gastroenterology and Hepatology Eastern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Kemp","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Lubel","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology Eastern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,12]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"1","volume-title":"The Gastroenterology Society of Australia\/Australian Liver Association","author":"Zekry A","year":"2013"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.4.571"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2007.12.003"},{"key":"e_1_2_5_5_1","first-page":"1489","volume-title":"Sleisenger and Fordtran: Gastrointestinal and Liver Disease: Pathophysiology\/Diagnosis\/Management","author":"Feldman M","year":"2010"},{"key":"e_1_2_5_6_1","first-page":"773","article-title":"Are there any alternative methods to hepatic venous pressure? 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