{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:20:53Z","timestamp":1765887653733},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T00:00:00Z","timestamp":1423008000000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There are limited clinical data on enteric fever in the Pacific and New Zealand (<jats:styled-content style=\"fixed-case\">NZ<\/jats:styled-content>) compared with the Indian subcontinent (<jats:styled-content style=\"fixed-case\">ISC<\/jats:styled-content>) and South\u2010East Asia (<jats:styled-content style=\"fixed-case\">SEA<\/jats:styled-content>). Our objective was to describe enteric fever in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>uckland \u2013 a large <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific city, focusing on disease acquired in these regions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed enteric fever cases hospitalised in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>uckland from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2005 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Microbiologically confirmed <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> was identified in 162 patients. Travel regions: <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific, 40 cases (25%) (<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>amoa, 38; <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>iji, two), <jats:styled-content style=\"fixed-case\">ISC<\/jats:styled-content>, 72 (44%), <jats:styled-content style=\"fixed-case\">SEA<\/jats:styled-content>, seven (4%), other, three (2%), no travel, 40 (25%). Enteric fever rates for <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>uckland resident travellers were: <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndia 50.3\/100\u2009000; <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>amoa 19.7\/100\u2009000.All <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific cases were <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content><jats:italic>almonella<\/jats:italic>\u2005<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>yphi. Of local isolates (without travel history), 38 were <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>yphi (36 fully susceptible, one multi\u2010drug resistant (<jats:styled-content style=\"fixed-case\">MDR<\/jats:styled-content>) + nalidixic acid resistant (<jats:styled-content style=\"fixed-case\">NAR<\/jats:styled-content>), one unknown) and two <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>aratyphi (both <jats:styled-content style=\"fixed-case\">NAR<\/jats:styled-content>). Of non\u2010Pacific travel, 56\/82 (69%) isolates were <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>yphi, the remainder <jats:styled-content style=\"fixed-case\"><jats:italic>S<\/jats:italic><\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>aratyphi (15 isolates were fully susceptible, only 1% were <jats:styled-content style=\"fixed-case\">MDR<\/jats:styled-content>). Significant associations of serotype and antibiotic resistance with different travel regions and similarity of phage types (local and <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific) were observed.<\/jats:p><\/jats:sec><jats:sec><jats:label \/><jats:p>Headache, vomiting and acute kidney injuries were more frequent with Pacific travel, while abdominal distension and cholecystitis with local disease. Shorter duration of treatment in the Pacific group was seen despite length of stay in hospital not being reduced. Local cases were associated with longer hospital admissions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>One half of cases in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>uckland are acquired either from <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific or locally. <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>imilarities mean that disease acquired locally is likely of <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific origin.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.12644","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T07:23:30Z","timestamp":1416295410000},"page":"148-155","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Enteric fever in the <scp>P<\/scp>acific: a regional retrospective study from <scp>A<\/scp>uckland, <scp>N<\/scp>ew <scp>Z<\/scp>ealand"],"prefix":"10.1111","volume":"45","author":[{"given":"R. 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