{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T06:40:21Z","timestamp":1767163221412,"version":"build-2238731810"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T00:00:00Z","timestamp":1425340800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Options for treatment of elderly patients with multiple myeloma have expanded substantially following the development of immunomodulatory drugs (\n                    <jats:styled-content style=\"fixed-case\">IMiD<\/jats:styled-content>\n                    ), proteasome inhibitors and with enhancement in safety of high\u2010dose therapy and autologous stem cell transplant (\n                    <jats:styled-content style=\"fixed-case\">HDT<\/jats:styled-content>\n                    +\n                    <jats:styled-content style=\"fixed-case\">ASCT<\/jats:styled-content>\n                    ). The recognition of biological heterogeneity among elderly patients has made delivery of therapy more challenging. An individualised approach to treatment selection is recommended in an era in which highly efficacious treatment options are available for transplant\u2010ineligible patients. Here, we summarise recommendations for patients who are considered unsuitable for\n                    <jats:styled-content style=\"fixed-case\">HDT<\/jats:styled-content>\n                    +\n                    <jats:styled-content style=\"fixed-case\">ASCT<\/jats:styled-content>\n                    , including pretreatment considerations, and induction, maintenance and supportive care therapies.\n                  <\/jats:p>","DOI":"10.1111\/imj.12688","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T05:49:33Z","timestamp":1425361773000},"page":"335-343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Treatment of patients with multiple myeloma who are not eligible for stem cell transplantation: position statement of the myeloma foundation of\n                    <scp>A<\/scp>\n                    ustralia\n                    <scp>M<\/scp>\n                    edical and\n                    <scp>S<\/scp>\n                    cientific\n                    <scp>A<\/scp>\n                    dvisory\n                    <scp>G<\/scp>\n                    roup"],"prefix":"10.1111","volume":"45","author":[{"given":"H.","family":"Quach","sequence":"first","affiliation":[{"name":"Department of Haematology St Vincent's Hospital  Melbourne Victoria Australia"},{"name":"Faculty of Medicine Dentistry and Health Sciences The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Joshua","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Haematology Royal Prince Alfred Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ho","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Haematology Royal Prince Alfred Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Szer","sequence":"additional","affiliation":[{"name":"Department of Clinical Haematology and BMT Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Spencer","sequence":"additional","affiliation":[{"name":"Department of Haematology The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Harrison","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Dentistry and Health Sciences The University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Haematology Peter MacCallum Cancer Centre  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Mollee","sequence":"additional","affiliation":[{"name":"Amyloidosis Centre and Department of Haematology Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"School of Medicine University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Dentistry and Health Sciences The University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Clinical Haematology and BMT Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Horvath","sequence":"additional","affiliation":[{"name":"Department of Haematology South Australia Pathology  Adelaide South Australia 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