{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:24:58Z","timestamp":1740126298952,"version":"3.37.3"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,5,8]],"date-time":"2015-05-08T00:00:00Z","timestamp":1431043200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009947","name":"Merck Sharp & Dohme","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009947","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001316","name":"Abbott","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Janssen"},{"name":"Ferring"},{"name":"Nycomed"},{"name":"Orphan"},{"name":"Shire"},{"DOI":"10.13039\/100002429","name":"Amgen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100002429","id-type":"DOI","asserted-by":"crossref"}]},{"name":"ImmunosanT"},{"name":"AstraZeneca"},{"name":"Takeda"},{"name":"Hospira"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Colonoscopy is an invasive procedure and a limited resource. It is therefore desirable to restrict its use to those in whom it yields an important diagnosis, without missing pathology in others.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to determine whether standard clinical criteria can be used to reliably distinguish when colonoscopy is advisable in women 30 years and younger.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective audit was performed at a single centre of 100 consecutive colonoscopies performed in women 30 years old and younger. The indications for the colonoscopy were recorded, and divided into clear and relative indications. The primary outcome of whether an endoscopic diagnosis was made was compared between the two groups. Clear indications for colonoscopy included overt rectal bleeding, elevated inflammatory markers, anaemia, iron deficiency and strong family history of colorectal cancer. Relative indications included abdominal pain or discomfort, bloating and altered bowel habit\/motions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age was 23 years. Sixty women had both relative and clear indications. Eleven had only clear indications and 28 only relative indications. Altogether, 58 colonoscopies were normal, and 17 showed inflammatory bowel disease. No subject with only relative indications had an abnormal finding (0\/28). The diagnostic yield was significantly different between those with only relative indications (0%) versus those with at least one clear indication (59%; <jats:italic>P<\/jats:italic> &lt; 0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Standard clinical criteria can be used to restrict safely the use of colonoscopy in young women. This will avoid performing procedures in people without clear indications, saving costs, resources and complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.12703","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T03:33:08Z","timestamp":1422934388000},"page":"492-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical triage for colonoscopy is useful in young women"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7748-2165","authenticated-orcid":false,"given":"K. D.","family":"Williamson","sequence":"first","affiliation":[{"name":"Translational Gastroenterology Unit John Radcliffe Hospital  Oxford UK"},{"name":"Nuffield Department of Medicine Oxford University  Oxford UK"},{"name":"Discipline of Medicine University of Adelaide  Adelaide Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Steveling","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Knappschaftskrankenhaus  P\u00fcttlingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Holtmann","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Princess Alexandra Hospital  Brisbane Australia"},{"name":"Faculty of Medicine and Biomedical Sciences University of Queensland  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Schoeman","sequence":"additional","affiliation":[{"name":"Gastrointestinal Endoscopic Services Department of Gastroenterology and Hepatology Royal Adelaide Hospital  South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Andrews","sequence":"additional","affiliation":[{"name":"Discipline of Medicine University of Adelaide  Adelaide Australia"},{"name":"Inflammatory Bowel Disease Service and Education Department of Gastroenterology and Hepatology Royal Adelaide Hospital  South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.01.011"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(03)80005-6"},{"volume-title":"Guidelines for the Prevention, Early Detection and Management of Colorectal Cancer","year":"2005","author":"Australian Cancer Network Colorectal Cancer Guidelines Revision Committee","key":"e_1_2_7_4_1"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/854984"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.06.037"},{"issue":"1","key":"e_1_2_7_7_1","first-page":"S1","article-title":"An evidence\u2010based position statement on the management of irritable bowel syndrome","volume":"104","author":"American College of Gastroenterology Task Force on Irritable Bowel Syndrome","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i44.7007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520701679116"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.02.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2014.08.033"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2006.04753.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.08.016"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06338.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.47.4.506"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fimj.12703","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.12703","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T17:08:38Z","timestamp":1695575318000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.12703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/imj.12703"],"URL":"https:\/\/doi.org\/10.1111\/imj.12703","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"type":"print","value":"1444-0903"},{"type":"electronic","value":"1445-5994"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"2014-07-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-01-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-05-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}