{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:59:52Z","timestamp":1791910792165,"version":"4.3.4"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,5]],"date-time":"2017-03-05T00:00:00Z","timestamp":1488672000000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) is the most common arrhythmia occurring in 2% of the population. It is known that<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>increases morbidity and limits quality of life. The<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc<\/jats:styled-content>score (congestive heart failure\/left ventricular dysfunction, hypertension, age \u226575 (doubled), diabetes, stroke (doubled), vascular disease, age 65\u201374 and sex category (female)) is widely used to assess thrombotic complications. The<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc<\/jats:styled-content>score was not used until now in predicting the effectiveness of electrical cardioversion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the value of<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc<\/jats:styled-content>score in predicting unsuccessful electrical cardioversion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed 258 consecutive patients with persistent<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>who underwent electrical cardioversion between January 2012 and April 2016 in a Cardiology University Centre in Poland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 3500 hospitalised patients with<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>, 258 (mean age 64\u2009\u00b1\u200911\u2009years, 64% men) underwent electrical cardioversion. The<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc<\/jats:styled-content>score in analysed population (258 patients) was 2.5\u2009\u00b1\u20091.7 (range 0\u20138), and the<jats:styled-content style=\"fixed-case\">HAS\u2010BLED<\/jats:styled-content>(hypertension, abnormal liver or renal function, stroke, bleeding, labile international normalised ratio, elderly, drugs or alcohol) was 1\u2009\u00b1\u20090.9 (range 0\u20134). Electrical cardioversion was unsuccessful in 12%. Factors associated with unsuccessful cardioversion were age (<jats:italic>P<\/jats:italic>\u2009=\u20090.0005), history of ischaemic stroke (<jats:italic>P<\/jats:italic>\u2009=\u20090.04), male gender (<jats:italic>P<\/jats:italic>\u2009=\u20090.01) and<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VAS<\/jats:styled-content>c score (<jats:italic>P<\/jats:italic>\u2009=\u20090.002). The<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VAS<\/jats:styled-content>c score in patients who had unsuccessful cardioversion was higher compared to patients who had successful cardioversion \u2013 3.5 versus 2.4 (<jats:italic>P<\/jats:italic>\u2009=\u20090.001). In the logistic regression model, if the<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VAS<\/jats:styled-content>c score increases by 1, the odds of unsuccessful cardioversion increase by 39% (odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) 1.39; confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>): 1.12\u20131.71;<jats:italic>P<\/jats:italic>\u2009=\u20090.002). The odds of unsuccessful cardioversion are three times higher in patients with a<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VAS<\/jats:styled-content>c score\u2009\u2265\u20092 than in patients with a<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc score<\/jats:styled-content>of 0 or 1 (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>3.06;<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.03\u20139.09;<jats:italic>P<\/jats:italic>\u2009=\u20090.044).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The<jats:styled-content style=\"fixed-case\">CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc<\/jats:styled-content>score routinely used in thromboembolic risk assessment may be a simple, easy and reliable scoring system that can be used to predict unsuccessful electrical cardioversion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.13319","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T08:36:25Z","timestamp":1478766985000},"page":"275-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["<scp>CHA<sub>2<\/sub>DS<sub>2<\/sub>VASc<\/scp>score predicts unsuccessful electrical cardioversion in patients with persistent atrial fibrillation"],"prefix":"10.1111","volume":"47","author":[{"given":"Elzbieta","family":"Mlodawska","sequence":"first","affiliation":[{"name":"Department of Cardiology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Tomaszuk\u2010Kazberuk","sequence":"additional","affiliation":[{"name":"Department of Cardiology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Lopatowska","sequence":"additional","affiliation":[{"name":"Department of Cardiology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Kaminski","sequence":"additional","affiliation":[{"name":"Department of Cardiology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wlodzimierz J.","family":"Musial","sequence":"additional","affiliation":[{"name":"Department of Cardiology Medical University of Bialystok Bialystok Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs253"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq278"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.20452\/pamw.2965","article-title":"CHA2DS2VASc and R2CHA2DS2VASc scores have predictive value in patients with acute coronary syndrome","volume":"125","author":"Kiliszek M","year":"2015","journal-title":"Pol Arch Med 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