{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T18:33:19Z","timestamp":1759775599605},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T00:00:00Z","timestamp":1487116800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Transoesophageal endobronchial ultrasound (<jats:styled-content style=\"fixed-case\">EBUS<\/jats:styled-content>) video\u2010bronchoscope insertion provides pulmonologists access to conduct endoscopic fine\u2010needle aspiration (<jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content>) of mediastinal lymph node (<jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content>) lesions and also assist in lung cancer staging by sampling left adrenal gland (<jats:styled-content style=\"fixed-case\">LAG<\/jats:styled-content>) lesions. Limited literature has described additional diagnostic value whilst maintaining patient safety.<\/jats:p><jats:p>To elicit whether combining endoscopic transoesophageal fine\u2010needle aspiration using convex probe bronchoscope (EUS\u2010B\u2010FNA) and EBUS bronchoscopy enhances the diagnostic yield of mediastinal nodal staging in lung cancer, whilst maintaining safety.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All eligible patients with paraoesophageal lesions on thoracic computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) underwent pulmonologist\u2010performed <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> at two tertiary centres and were included in this prospective observational cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> sampling was performed at 69 mediastinal <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> lesion sites, including 17 sites inaccessible to bronchoscopic sampling. Four <jats:styled-content style=\"fixed-case\">LAG<\/jats:styled-content> lesions were sampled via <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content>. There were no complications. <jats:styled-content style=\"fixed-case\">EBUS\u2010TBNA<\/jats:styled-content> was augmented by <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> because of accessibility of sampling lesions otherwise unamenable bronchoscopically, thereby increasing diagnostic utility. Diagnostic sensitivity of <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> for malignancy in mediastinal <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> lesions was 88% (51 of 58). For mediastinal <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> lesions not amenable to <jats:styled-content style=\"fixed-case\">EBUS\u2010TBNA<\/jats:styled-content>, the sensitivity for diagnosis of malignancy via <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> was 88% (15 of 17). Diagnostic sensitivity of <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> for malignancy in <jats:styled-content style=\"fixed-case\">LAG<\/jats:styled-content> lesions was 50% (2 of 4).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010B\u2010<jats:styled-content style=\"fixed-case\">FNA<\/jats:styled-content> is a precise and safe approach in the evaluation and staging of lung cancer when performed by a pulmonologist. It complements and increases the diagnostic utility of <jats:styled-content style=\"fixed-case\">EBUS\u2010TBNA<\/jats:styled-content> by further coverage of mediastinal <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> stations and access to <jats:styled-content style=\"fixed-case\">LAG<\/jats:styled-content> lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.13330","type":"journal-article","created":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T04:15:09Z","timestamp":1479356109000},"page":"205-210","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Pulmonologist\u2010performed transoesophageal sampling for lung cancer staging using an endobronchial ultrasound video\u2010bronchoscope: an Australian experience"],"prefix":"10.1111","volume":"47","author":[{"given":"Hari","family":"Wimaleswaran","sequence":"first","affiliation":[{"name":"Deparment of Respiratory Medicine Royal Melbourne 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