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There have been significant changes in recommended vaccinations since the previously published recommendations in 2008. We provide current recommendations to help Australian and New Zealand clinicians in the prevention of sepsis in patients with asplenia and hyposplenia. The guideline includes Australian epidemiological data, preferred diagnostic techniques and recommendations for optimal antimicrobial prophylaxis and vaccination protocols.<\/jats:p>","DOI":"10.1111\/imj.13348","type":"journal-article","created":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T13:02:38Z","timestamp":1481115758000},"page":"848-855","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Spleen Australia guidelines for the prevention of sepsis in patients with asplenia and hyposplenism in Australia and New Zealand"],"prefix":"10.1111","volume":"47","author":[{"given":"Kudzai","family":"Kanhutu","sequence":"first","affiliation":[{"name":"Victorian Infectious Diseases Service Royal Melbourne Hospital  Melbourne Victoria Australia"},{"name":"Dentistry and Health Sciences, Faculty of Medicine The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope","family":"Jones","sequence":"additional","affiliation":[{"name":"Spleen Australia, Department of Infectious Diseases Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen C.","family":"Cheng","sequence":"additional","affiliation":[{"name":"Spleen Australia, Department of Infectious Diseases Alfred Health  Melbourne Victoria Australia"},{"name":"Infection Prevention and Healthcare Epidemiology Unit Alfred Health  Melbourne Victoria Australia"},{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Grannell","sequence":"additional","affiliation":[{"name":"Spleen Australia, Department of Infectious Diseases Alfred Health  Melbourne Victoria Australia"},{"name":"Pharmacy Department Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Best","sequence":"additional","affiliation":[{"name":"University of Auckland and Starship Children's Hospital  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Spelman","sequence":"additional","affiliation":[{"name":"Spleen Australia, Department of Infectious Diseases Alfred Health  Melbourne Victoria Australia"},{"name":"Microbiology Unit, Department of Pathology Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2006.03775.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-219"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2007.01579.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08843.x"},{"key":"e_1_2_7_6_1","unstructured":"Public Health Agency of Canada. 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