{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T22:18:30Z","timestamp":1780611510327,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T00:00:00Z","timestamp":1491868800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>East Timor is a developing country and is a close neighbour of Australia. The prevalence of cardiac disease is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To describe the prevalence and patterns of cardiac disease in patients attending the first cardiology service of Timor\u2010Leste.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional retrospective analysis was performed of demographic and clinical data of 474 unique patients referred to outpatient cardiology clinics conducted in East Timor from 2003 to 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 29.9\u2009\u00b1\u200918.5\u2009years, with females significantly younger than males (28.8\u2009\u00b1\u200916.9 vs 32.3\u2009\u00b1\u200920.6\u2009years). Congenital cardiac disease patients were the youngest (15.5\u2009\u00b1\u200913.9\u2009years) and cardiomyopathy patients the oldest (46.7\u2009\u00b1\u200917.8\u2009years).<\/jats:p><jats:p>Of patients with rheumatic heart disease, the majority had mitral stenosis (59.4%) and multi\u2010valvular involvement (61.6%). Of note, 28.3% of patients with rheumatic heart disease presented with severe mitral stenosis. Amongst congenital heart disease patients, the most common diagnosis was atrial or ventricular septal defects (61% combined). A total of 19.2% of patients either required immediate referral for intervention or palliation for their cardiac disease. Patients referred to Australia for treatment were significantly younger (19.7\u2009\u00b1\u200911.7\u2009years) than all other outcome groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Amongst young East Timorese, rheumatic heart disease and unrepaired congenital cardiac defects impose a significant burden. One\u2010fifth of patients present to clinics with severe disease requiring urgent referral for surgery or palliation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.13381","type":"journal-article","created":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T06:03:19Z","timestamp":1485928999000},"page":"423-428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Heart disease in East Timor: cross\u2010sectional analysis of 474 patients attending Timor\u2010Leste's first cardiology service"],"prefix":"10.1111","volume":"47","author":[{"given":"Elizabeth D.","family":"Paratz","sequence":"first","affiliation":[{"name":"East Timor Hearts Fund  Melbourne Victoria Australia"},{"name":"St Vincent's Health Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noel","family":"Bayley","sequence":"additional","affiliation":[{"name":"East Timor Hearts Fund  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,11]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"WHO. 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