{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T01:15:15Z","timestamp":1772500515949,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the epidemiology of non\u2010typhoid<jats:italic>Salmonella<\/jats:italic>(NTS) infection in the Australian Capital Territory (ACT), including factors associated with hospitalisation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective descriptive and observational study of culture\u2010confirmed NTS infections using data collected from ACT public health, public pathology and hospital services in the period 2003\u20132012. Outcome measures include incidence and NTS serotype for total reported and hospitalised cases and focus of infection, complications and antibiotic susceptibility for hospitalised cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1469 cases of NTS infection were reported, with the crude annual incidence increasing from 24.4 to 61.3 cases per 100\u2009000 population; 14% were hospitalised, representing an incidence of 5.9 hospitalisations per 100\u2009000 population, without significant change over time. Hospitalisation incidence peaked at the extremes of age. Comorbid disease and age \u2265 80 years were associated with complications during hospitalisation.<jats:italic>Salmonella<\/jats:italic>serotype Typhimurium was the most common serotype, accounting for 64% of NTS. Independent risk factors for invasive disease included non\u2010<jats:italic>S.<\/jats:italic>Typhimurium serotype (aRR 5.46, 95%CI 1.69\u201317.65<jats:italic>P<\/jats:italic>= 0.005), ischaemic heart disease (aRR 4.18, 95%CI 1.20\u201314.60<jats:italic>P<\/jats:italic>= 0.025) and haematological malignancy (aRR 6.93, 95%CI 2.54\u201318.94<jats:italic>P<\/jats:italic>&lt; 0.001). Among hospitalised patients, resistance to ampicillin, ceftriaxone, trimethoprim\u2010sulfamethoxazole and quinolones was 9.9%, 0%, 4.4% and 2.5% respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>NTS notifications in the ACT have increased over time, with outbreaks of food\u2010borne disease contributing to this increase. Crude age\u2010specific incidence is highest in the very young, while rates of hospitalisation are highest in the elderly. Comorbid disease and infection with a non\u2010<jats:italic>S.<\/jats:italic>Typhimurium serotype were associated with complicated NTS disease course. Antimicrobial resistance in NTS is low and has not increased over time.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.13625","type":"journal-article","created":{"date-parts":[[2017,10,2]],"date-time":"2017-10-02T08:02:35Z","timestamp":1506931355000},"page":"316-323","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Epidemiology of non\u2010typhoid<i>Salmonella<\/i>infection in the Australian Capital Territory over a 10\u2010year period"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9846-1929","authenticated-orcid":false,"given":"Heather L.","family":"Wilson","sequence":"first","affiliation":[{"name":"Canberra Hospital and Health Services Canberra Australian Capital Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina J.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Canberra Hospital and Health Services Canberra Australian Capital Territory Australia"},{"name":"Australian National University Medical School Canberra Australian Capital Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron R. M.","family":"Moffatt","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology and Public Health, Research School of Population Health Australian National University Canberra Australian Capital Territory Australia"},{"name":"OzFoodNet, Health Protection Service, ACT Government Health Directorate Canberra Australian Capital Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001921"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/381580"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S095026880006711X"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00002-15"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e32830f453a"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"E601","DOI":"10.33321\/cdi.2015.39.56","article-title":"New surveillance case definition","volume":"39","year":"2015","journal-title":"Commun Dis Intell Q Rep"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_6_9_1","unstructured":"3105.0.65.001 \u2010 Australian Historical Population Statistics 2014. 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