{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:42:57Z","timestamp":1790127777100,"version":"4.0.1"},"reference-count":16,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T00:00:00Z","timestamp":1565049600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Frailty is common among acute hospital patients and might adversely affect recovery from inpatient cardiac arrest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess the relationship between hospital admission characteristics, including frailty, and discharge outcome after in\u2010hospital cardiac arrest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospectively collected data were retrospectively analysed for all separations from a tertiary hospital during 2008\u20132017 that involved rapid response team attendance for cardiac arrest. Hospital Frailty Risk Score (HFRS) and Charlson index of comorbidity were calculated from \u2018primary\u2019 and \u2018associated\u2019 International Classification of Diseases, 10th revision, Australian Modification diagnoses. HFRS \u22655 was taken to signify frailty. Discharge home from hospital and death in hospital were modelled using logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 388 in\u2010hospital arrest patients: 91% were aged \u226550 years, 34% were previously discharged in the past 6 months, 66% were unplanned admissions, 63% were non\u2010cardiology\u2010cardiothoracic admissions, 45% had a Charlson comorbidity index \u22652 and 19% were identified as frail. Discharge home occurred in 22%, discharge to another hospital 17% and death 62%. Of the frail patients, only 3 (4%) were discharged home, 12 (17%) were discharged to another hospital and 57 (79%) died in hospital. Fewer frail patients were discharged home compared with non\u2010frail patients (4 vs 26%; odds ratio (OR) 0.13,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001). On multivariable analysis, patients were less likely to be discharged home if they had frailty (OR 0.24,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.02), age \u2265 50 years (OR 0.36,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01), non\u2010cardiology\u2010cardiothoracic unit admission (OR 0.40,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001) and unplanned admission (OR 0.57,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.04). Frail patients discharged to another hospital spent a median of 15 days (interquartile range 11\u201323) in the hospital post\u2010arrest before leaving to continue inpatient care elsewhere. Frailty was associated with death in hospital on univariate analysis (79 vs 58%; OR 2.80,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001) but not after controlling for other factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Frail patients are unlikely to make a good recovery after in\u2010hospital arrest. This should be taken into account when planning care with patients and their families.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/imj.14159","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T00:37:06Z","timestamp":1541723826000},"page":"978-985","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Frailty is associated with reduced prospect of discharge home after in\u2010hospital cardiac arrest"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9356-2285","authenticated-orcid":false,"given":"Roger J.","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine St Vincent\u2019s Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Reid","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine St Vincent\u2019s Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Santamaria","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine St Vincent\u2019s Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)62167-9"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.050051"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1655756"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.07.012"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1007\/s00134-014-3253-4","article-title":"Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study","volume":"40","author":"Le Maguet P","year":"2014","journal-title":"Intensive Care Med"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30668-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003126"},{"key":"e_1_2_6_10_1","first-page":"71","article-title":"Rapid response team diagnoses: frequencies and related hospital mortality","volume":"19","author":"Smith RJ","year":"2017","journal-title":"Crit Care Resusc"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_6_12_1","unstructured":"Department of Health & Human Services (Victoria). 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