{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:30:03Z","timestamp":1749429003516,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Adults with human immunodeficiency virus (HIV) infection commonly experience fractures and have a high prevalence of osteoporosis. The reasons for low bone mineral density (BMD) in HIV patients are multifactorial and there are now guidelines for screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aims of this study were to determine the screening practices for osteoporosis at this sexual health clinic, the prevalence of osteoporosis and to examine the risk factors for bone disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective cohort study of all HIV patients attending the Sunshine Coast Health Service District Sexual Health Clinic. Through chart review we collected the following details: patient demographics, co\u2010morbid conditions, HIV status and anti\u2010retroviral therapy, BMD screening, fractures, screening for secondary causes of bone disease and treatment interventions for osteoporosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 243 patients with HIV attended the sexual health clinic. Of these, 149 met screening criteria for BMD assessment and 93 (61%) of those eligible underwent BMD examination. In those who had a BMD performed, 13 (19%) had sustained a previous fracture, 28 (30%) had osteoporosis and 42 (45%) had osteopenia. In the osteoporosis group, 21 (78%) were treated with vitamin D and calcium, 7 (26%) had a change in ART, 19 (68%) were treated with anti\u2010resorptive therapy and 9 received testosterone replacement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this cohort, there was a high prevalence of low bone mass and BMD screening rates of 60%. Our results highlight the importance of this condition and the need to improve screening and availability of BMD assessment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.14357","type":"journal-article","created":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T06:54:51Z","timestamp":1557730491000},"page":"1119-1124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of screening practices for low bone mass and prevalence of osteoporosis and fractures in people living with human immunodeficiency virus attending a sexual health clinic"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4829-9905","authenticated-orcid":false,"given":"Natalie","family":"Davidson","sequence":"first","affiliation":[{"name":"Infectious Diseases Department Sunshine Coast University Hospital  Sunshine Coast Region Queensland Australia"},{"name":"School of Medicine, University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Sowden","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department Sunshine Coast University Hospital  Sunshine Coast Region Queensland Australia"},{"name":"Microbiology Department, Pathology Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32801022eb"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328361d241"},{"key":"e_1_2_6_4_1","first-page":"1525","article-title":"Comorbidities among US patients with prevalent HIV infection\u2010a trend analysis","volume":"216","author":"Gallant J","year":"2017","journal-title":"J Infect Dis"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/656412"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/656417"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328328f789"},{"key":"e_1_2_6_8_1","article-title":"The efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in antiretroviral regimens for HIV\u20101 therapy: meta\u2010analysis","volume":"95","author":"Wang H","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S2055-6640(20)30248-X","article-title":"Tenofovir alafenamide versus tenofovir disoproxil fumarate: is there a true difference in efficacy and safety?","volume":"4","author":"Hill AHS","year":"2018","journal-title":"J Virus Erad"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12322"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis199"},{"key":"e_1_2_6_12_1","first-page":"1721","article-title":"FRAX \u2013 fracture risk assessment tool by WHO","volume":"19","author":"Orimo H","year":"2009","journal-title":"Clin Calcium"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1545109711418832"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2009.tb02421.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ010"},{"key":"e_1_2_6_16_1","unstructured":"MIllsT AJ DiPerriG et al. Switching from a tenofovir disoproxil fumarate (TDF)\u2010based regimen to a tenofovir alafenamide (TAF)\u2010based regimen: data in virologically suppressed adults through 48 weeks of treatment. 8th International AIDS Society Conference on HIV Pathogenesis Treatment and Prevention;2015."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12123"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1097\/QAD.0000000000001911","article-title":"Zoledronic acid is superior to tenofovir disoproxil fumarate\u2010switching for low bone mineral density in adults with HIV","volume":"32","author":"Hoy JF","year":"2018","journal-title":"AIDS"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60752-0"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fimj.14357","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.14357","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/imj.14357","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.14357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T17:20:43Z","timestamp":1694193643000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.14357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/imj.14357"],"URL":"https:\/\/doi.org\/10.1111\/imj.14357","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"type":"print","value":"1444-0903"},{"type":"electronic","value":"1445-5994"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"2018-09-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}