{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:48:11Z","timestamp":1790657291579,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T00:00:00Z","timestamp":1605830400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT) can help reverse stroke symptoms in selected patients but are both time sensitive interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To report current stroke reperfusion rates and quality measures as well as trends over time in New Zealand.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Since 2015 New Zealand treatment centres have been mandated to enter prospectively all IVT and EVT patients into a low\u2010cost National Stroke Register. Data were cleaned, and missing data added where possible through contact with individual hospitals. Main outcomes include treatment delays, vital status at day 7 and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 2018, there were 719 of 7173 (10.0%) patients with ischaemic stroke or stroke unspecified treated with IVT, up from 389 of 5963 (6.5%) patients in 2015 (<jats:italic>P<\/jats:italic> &lt;\u20090.001), with no change in day 7 mortality (<jats:italic>P<\/jats:italic> =\u20090.63) or sICH rate (<jats:italic>P<\/jats:italic> =\u20090.22). Median (interquartile range (IQR)) door\u2010to\u2010needle times decreased from 65 (47\u201389) min in 2017 to 59 (40\u201384) min in 2018 (<jats:italic>P<\/jats:italic> =\u20090.022), and patients treated within 60 min increased from 40 to 51% (<jats:italic>P<\/jats:italic> &lt;\u20090.001). In 2018, there were 243 (3.4%) patients treated with EVT up from 134\/6859 (1.9%) in 2017 (<jats:italic>P<\/jats:italic> &lt;\u20090.0001), with no change in 7\u2010day mortality (<jats:italic>P<\/jats:italic> =\u20090.39) or intracerebral haemorrhage (sICH) (<jats:italic>P<\/jats:italic> =\u20090.78). There was no significant change in onset\u2010to\u2010needle (<jats:italic>P<\/jats:italic> =\u20090.21), arrival\u2010to\u2010groin (<jats:italic>P<\/jats:italic> =\u20090.28) or onset\u2010to\u2010reperfusion time (<jats:italic>P<\/jats:italic> =\u20090.32).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Stroke reperfusion rates in New Zealand are continuously rising with no associated increase in complications. More patients are being treated faster upon hospital arrival but there remains room for further improvement in reducing onset to treatment delays.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.14682","type":"journal-article","created":{"date-parts":[[2019,11,10]],"date-time":"2019-11-10T07:59:26Z","timestamp":1573372766000},"page":"1367-1372","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Trends in stroke reperfusion treatment and outcomes in New Zealand"],"prefix":"10.1111","volume":"50","author":[{"given":"Fredrik","family":"Hedlund","sequence":"first","affiliation":[{"name":"Department of Medicine University of Otago  Wellington New Zealand"},{"name":"Department of Neuroscience, Neurology Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Leighs","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Otago  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Alan","family":"Barber","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Lundstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Neurology Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teddy Y.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurology Christchurch Hospital  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3223-3330","authenticated-orcid":false,"given":"Annemarei","family":"Ranta","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Otago  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0134609","article-title":"30\u2010year trends in stroke rates and outcome in Auckland, New Zealand (1981\u20132012): a multi\u2010ethnic population\u2010based series of studies","volume":"10","author":"Feigin VL","year":"2015","journal-title":"PLoS One"},{"key":"e_1_2_7_3_1","first-page":"1477","article-title":"Projected stroke volumes to provide a 10\u2010year direction for New Zealand stroke services","volume":"131","author":"Ranta A","year":"2018","journal-title":"NZ Med J"},{"key":"e_1_2_7_4_1","first-page":"50","article-title":"Trends in New Zealand stroke IVT treatment rates","volume":"130","author":"Liu Q","year":"2017","journal-title":"NZ Medizinhist J"},{"key":"e_1_2_7_5_1","first-page":"6","article-title":"Endovascular clot retrieval for acute ischemic stroke in New Zealand","volume":"131","author":"Burnell AL","year":"2018","journal-title":"NZ Med J"},{"key":"e_1_2_7_6_1","article-title":"Helsinki stroke model is transferrable with \u201creal\u2010world\u201d resources and reduced stroke thrombolysis delay to 34\u2009min in Christchurch","volume":"9","author":"Wu TY","year":"2018","journal-title":"Front Neurol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13557"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804656"},{"key":"e_1_2_7_9_1","first-page":"50","article-title":"Ranta,a. provision of stroke thrombolysis services in New Zealand: changes between 2011 and 2016","volume":"130","author":"Liu Q","year":"2017","journal-title":"NZ Med J."},{"key":"e_1_2_7_10_1","unstructured":"Statistics New Zealand2013census data. [cited April 2019]. Available from URL:http:\/\/archive.stats.govt.nz\/Census\/2013-census\/data-tables\/dhb-tables.aspx"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"AWP406","DOI":"10.1161\/str.50.suppl_1.WP406","article-title":"New Zealand hospital stroke service provision: a National Survey","volume":"50","author":"Ranta A","year":"2019","journal-title":"Stroke"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fimj.14682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.14682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/imj.14682","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.14682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T20:41:18Z","timestamp":1693860078000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.14682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/imj.14682"],"URL":"https:\/\/doi.org\/10.1111\/imj.14682","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"value":"1444-0903","type":"print"},{"value":"1445-5994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"2019-08-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}