{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T15:44:54Z","timestamp":1790869494537,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nephrotic range proteinuria has been reported during the course of severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) and coronavirus disease (COVID\u201019). However, the pathological mechanisms underlying this manifestation are unknown. In this article, we present two cases of collapsing glomerulopathy (CG) associated with acute tubular necrosis during the course of COVID\u201019, and review the literature for similar reports. In our two cases, as in the 14 cases reported so far, the patients were of African ancestry. The 14 patients assessed had an APOL1 high\u2010risk genotype. At the end of the reported period, two patients had died and five patients were still requiring dialysis. The 16 cases detailed in the present report strongly argue in favour of a causal link between SARS\u2010CoV\u20102 infection and the occurrence of CG in patients homozygous for APOL1 high\u2010risk genotype for which the term COVID\u2010associated nephropathy (COVIDAN) can be put forward.<\/jats:p>","DOI":"10.1111\/imj.15041","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T04:02:51Z","timestamp":1608782571000},"page":"1551-1558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["<scp>COVID\u201019<\/scp>\u2010associated collapsing glomerulopathy: a report of two cases and literature review"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6249-9837","authenticated-orcid":false,"given":"Hassan","family":"Izzedine","sequence":"first","affiliation":[{"name":"Department of Nephrology Peupliers Private Hospital, Ramsay G\u00e9n\u00e9rale de Sant\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Brocheriou","sequence":"additional","affiliation":[{"name":"Department of Pathology Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Arzouk","sequence":"additional","affiliation":[{"name":"Department of Kidney Transplantation Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Seilhean","sequence":"additional","affiliation":[{"name":"Department of Neuropathology Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7607-2057","authenticated-orcid":false,"given":"Philippe","family":"Couvert","sequence":"additional","affiliation":[{"name":"Department of Endocrine &amp; Oncology Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re, UMR\u2010S1166  Paris France"},{"name":"Service de Biochimie endocrinienne et oncologique, Sorbonne Universit\u00e9, Assistance publique\u2010H\u00f4pitaux de Paris, Groupement hospitalier Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Cluzel","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiovascular Radiology Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micheline","family":"Pha","sequence":"additional","affiliation":[{"name":"Service de Medecine Interne 2, Institut E3M Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ophelie","family":"Le Monnier","sequence":"additional","affiliation":[{"name":"Service de Medecine Interne 2, Institut E3M Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shadia","family":"Varnous","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Andreelli","sequence":"additional","affiliation":[{"name":"Department of Diabetology &amp; Metabolism, Institut E3M, ICAN Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahir","family":"Amoura","sequence":"additional","affiliation":[{"name":"Service de Medecine Interne 2, Institut E3M Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Mathian","sequence":"additional","affiliation":[{"name":"Service de Medecine Interne 2, Institut E3M Sorbonne University, Assistance Publique\u2010H\u00f4pitaux de Paris, Groupement Hospitalier Piti\u00e9\u2013Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2001737"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.003"},{"key":"e_1_2_5_5_1","article-title":"Caution on kidney dysfunctions of 2019\u2010nCoV patients","author":"Wu M","year":"2020","journal-title":"medRxiv"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.03.001"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0002652020"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2020.04.002"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2020.04.017"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.04.006"},{"key":"e_1_2_5_11_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.kint.2020.04.022","article-title":"Tubuloreticular inclusions in COVID\u201019\u2010related collapsing glomerulopathy","volume":"98","author":"Gaillard F","year":"2020","journal-title":"Kidney Int"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2020.05.013"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2020050558"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012121180"},{"key":"e_1_2_5_15_1","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.xkme.2020.05.004","article-title":"COVID\u201019\u2013related glomerulopathy: a report of 2 cases of collapsing focal segmental glomerulosclerosis","volume":"2","author":"Magoon S","year":"2020","journal-title":"Kidney Med"},{"key":"e_1_2_5_16_1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.xkme.2020.05.005","article-title":"COVID\u201019\u2013associated collapsing focal segmental Glomerulosclerosis: a report of 2 cases","volume":"2","author":"Sharma Y","year":"2020","journal-title":"Kidney Med"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006030225"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc079008"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.11751111"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.11.017"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfx029"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002298"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2011040388"},{"key":"e_1_2_5_24_1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.5527\/wjn.v4.i2.295","article-title":"African origins and chronic kidney disease susceptibility in the human immunodeficiency virus era","volume":"4","author":"Kasembeli AN","year":"2015","journal-title":"World J Nephrol"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006050423"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.15041","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/imj.15041","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.15041","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T13:25:19Z","timestamp":1693747519000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.15041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":24,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/imj.15041"],"URL":"https:\/\/doi.org\/10.1111\/imj.15041","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"value":"1444-0903","type":"print"},{"value":"1445-5994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"2020-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}