{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T03:24:57Z","timestamp":1768533897718,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T00:00:00Z","timestamp":1652140800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Group B streptococcus (GBS) is a recognised perinatal and neonatal pathogen. There are reports of increasing GBS sepsis globally outside this demographic. North Queensland is part of tropical Australia, with a relatively high proportion of Indigenous Australians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To analyse the epidemiology of GBS bacteraemia and explore associated risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a 10\u2010year retrospective review of GBS bacteraemia in a tertiary facility in North Queensland, between 2010 and February 2020. Data variables collected included: demographics, risk factors, clinical source and outcomes. Multivariable logistic regression was performed to examine the association of indigenous status and other relevant clinical factors with mortality from GBS bacteraemia at 3 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 164 total cases, 123 were not pregnancy related. The annual rate of GBS bacteraemia for the indigenous population was 12.48 per 100 000 and 4.84 per 100 000 for the non\u2010indigenous population. Indigenous patients were more likely to have diabetes and chronic kidney disease compared with the non\u2010indigenous patients. Males (adjusted odds ratio (AOR) = 4.34; 95% CI 1.14\u221216.56; <jats:italic>P<\/jats:italic> = 0.031) and immunosuppressed patients (AOR = 11.49; 95% CI 2.73\u221248.42; <jats:italic>P<\/jats:italic> &lt; 0.001) were more likely to experience mortality at 3 months from GBS bacteraemia even after adjusting for other risk factors respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>GBS bacteraemia is deviating from being primarily a neonatal disease. While the indigenous population of North Queensland are disproportionately affected, the demographics affected differ. GBS appears to target the older non\u2010indigenous patients with greater comorbidities. In the non\u2010indigenous population, invasive GBS disease is an emerging issue. Three\u2010month mortality appears to be increased in males and the immunosuppressed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.15164","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:19:58Z","timestamp":1608596398000},"page":"800-807","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Group B streptococcal bacteraemia: changing trends in a tropical region of Australia"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9593-1921","authenticated-orcid":false,"given":"Mohammed","family":"Alizzi","sequence":"first","affiliation":[{"name":"School of Medicine James Cook University  Townsville Queensland Australia"},{"name":"Department of Infectious Diseases and Microbiology Townsville University Hospital  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romesh","family":"Rathnayake","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Microbiology Townsville University Hospital  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8340-1050","authenticated-orcid":false,"given":"Pirathaban","family":"Sivabalan","sequence":"additional","affiliation":[{"name":"School of Medicine James Cook University  Townsville Queensland Australia"},{"name":"Department of Infectious Diseases and Microbiology Townsville University Hospital  Townsville Queensland Australia"},{"name":"Faculty of Medicine University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theophilus I.","family":"Emeto","sequence":"additional","affiliation":[{"name":"College of Public Health, Medical and Veterinary Sciences James Cook University  Townsville Queensland Australia"},{"name":"Australian Institute of Tropical Health and Medicine James Cook University  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Norton","sequence":"additional","affiliation":[{"name":"School of Medicine James Cook University  Townsville Queensland Australia"},{"name":"Department of Infectious Diseases and Microbiology Townsville University Hospital  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00582-17"},{"key":"e_1_2_6_3_1","unstructured":"Australian Government Department of Health.Group B Streptococcus.2020[cited 2020 May 19]. 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