{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:16:40Z","timestamp":1781842600860,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lung transplantation is a recognised treatment for end\u2010stage lung disease due to bronchiectasis. Non\u2010cystic fibrosis (CF) bronchiectasis and CF are often combined into one cohort; however, outcomes for non\u2010CF bronchiectasis patients vary between centres, and in comparison with those for CF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare lung transplantation mortality and morbidity of bronchiectasis (non\u2010CF) patients with those with CF and other indications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of patients undergoing lung transplantation between 1 January 2008 and 31 December 2013. Time to and cause of lung allograft loss was censored on 1 April 2018. A case\u2010note review was conducted on a subgroup of 78 patients, to analyse hospital admissions as a marker of morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 341 patients underwent lung transplantation; 22 (6%) had bronchiectasis compared with 69 (20%) with CF. The 5\u2010year survival for the bronchiectasis group was 32%, compared with CF (69%), obstructive lung disease (OLD) (64%), pulmonary hypertension (62%) and ILD (55%) (<jats:italic>P<\/jats:italic> =\u20090.008). Lung allograft loss due to chronic lung allograft dysfunction with predominant infection was significantly higher in the bronchiectasis group at 2\u2009years. The rate of acute admissions was 2.24 higher in the bronchiectasis group when compared with OLD (<jats:italic>P<\/jats:italic> =\u20090.01). Patients with bronchiectasis spent 45.81\u2009days in hospital per person year after transplantation compared with 18.21\u2009days for CF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bronchiectasis patients in the present study had a lower 5\u2010year survival and poorer outcomes in comparison with other indications including CF. Bronchiectasis should be considered a separate entity to CF in survival analysis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.15256","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T10:59:09Z","timestamp":1614769149000},"page":"995-1001","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes of non\u2010cystic fibrosis\u2010related bronchiectasis post\u2010lung transplantation"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2086-743X","authenticated-orcid":false,"given":"Jessica L.","family":"Kennedy","sequence":"first","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital  Melbourne Victoria Australia"},{"name":"School of Medicine Dentistry and Health Science, Melbourne University  Melbourne Victoria Australia"},{"name":"Department of Respiratory and Sleep Medicine Austin Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital  Melbourne Victoria Australia"},{"name":"Department of Thoracic Medicine Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire M.","family":"Ellender","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital  Melbourne Victoria Australia"},{"name":"Department of Respiratory and Sleep Medicine Princess Alexandra Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Steinfort","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Martin","sequence":"additional","affiliation":[{"name":"Public Health and Preventative Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Smith","sequence":"additional","affiliation":[{"name":"Public Health and Preventative Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Snell","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Whitford","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Alfred Hospital  Melbourne Victoria 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