{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:11:15Z","timestamp":1791389475133,"version":"4.3.3"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T00:00:00Z","timestamp":1661904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Bronchiectasis is a serious, debilitating condition warranting specialist care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine if care provided in a tertiary hospital general respiratory clinic was guideline concordant and to validate the Bronchiectasis Severity Index (BSI) in the Australian context.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single\u2010centre ambispective study was conducted. The first stage involved a retrospective medical record audit between 1 January 2015 and 31 December 2016. All aspects of bronchiectasis management were reviewed. In the second prospective phase the cohort was followed for 4\u2009years to determine survival and the validity of the BSI determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 145 patients was included, with mean age of 65\u2009years (standard deviation\u00a0=\u00a016.6). The aetiology of bronchiectasis was explicitly documented for 58 (40%) patients, with potential causes identified in another 37 patients. Post\u2010infectious aetiologies were described in 62 (43%) patients. Most patients had lung function testing (<jats:italic>n<\/jats:italic> =\u2009142; 97%) and sputum culture results (<jats:italic>n<\/jats:italic> =\u2009120; 83%). Long\u2010term antibiotics were prescribed to 49 (34%) patients. Only patients culturing <jats:italic>Pseudomonas<\/jats:italic> spp. were prescribed inhaled antibiotics. Documentation regarding essential management recommendations was low, including airway clearance (46%), pneumococcal vaccination (27%) and written action plans (32%). Severe disease was common, with more than one\u2010third (34\u201348%) having BSI scores &gt;9. One\u2010fifth (21%) of the cohort died during the 4\u2010year follow\u2010up period. The BSI was significantly associated with mortality risk (odds ratio 7.7; 95% confidence interval\u00a0=\u00a03.1\u201319.3; <jats:italic>P<\/jats:italic> &lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our cohort had a high proportion of patients with severe disease and significant mortality; some, but not all, aspects of recommended care were delivered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.15730","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T08:06:48Z","timestamp":1646726808000},"page":"753-759","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Improving care for people with bronchiectasis: opportunities and challenges highlighted from service evaluation"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7736-4000","authenticated-orcid":false,"given":"Megan","family":"Rees","sequence":"first","affiliation":[{"name":"Department of Respiratory and Sleep Disorders Medicine The Royal Melbourne Hospital  Melbourne Victoria Australia"},{"name":"Department of Medicine, Royal Melbourne Hospital University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belinda","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Disorders Medicine The Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3555-6856","authenticated-orcid":false,"given":"Amy","family":"Pascoe","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Central Clinical School, The Alfred Hospital, Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Smallwood","sequence":"additional","affiliation":[{"name":"Department of Allergy, Immunology and Respiratory Medicine Central Clinical School, The Alfred Hospital, Monash University  Melbourne Victoria Australia"},{"name":"Department of Respiratory Medicine The Alfred Hospital  Melbourne Victoria 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bronchiectasis toolbox \u2013 a comprehensive website for the management of people with bronchiectasis","volume":"5","author":"Nicolson CH","year":"2017","journal-title":"Med Sci"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.316.7147.1771"}],"container-title":["Internal Medicine 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