{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:06:12Z","timestamp":1777575972571,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T00:00:00Z","timestamp":1666224000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cardiac light chain (AL) amyloidosis is a condition with a very poor prognosis. We report a retrospective analysis comparing the traditional melphalan and dexamethasone protocol with cyclophosphamide, bortezomib and dexamethasone in late\u2010stage cardiac AL amyloidosis. The primary end points were overall survival and haematological response. Both regimens provided meaningful responses in this difficult to treat patient group.<\/jats:p>","DOI":"10.1111\/imj.15926","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T01:09:40Z","timestamp":1666314580000},"page":"1826-1830","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of bortezomib, cyclophosphamide and dexamethasone in cardiac <scp>AL<\/scp> amyloidosis"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0306-3926","authenticated-orcid":false,"given":"Xavier","family":"Brennan","sequence":"first","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"},{"name":"University of New South Wales  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Withers","sequence":"additional","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Jabbour","sequence":"additional","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"},{"name":"University of New South Wales  Sydney New South Wales Australia"},{"name":"The Victor Chang Cardiac Research Institute  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Milliken","sequence":"additional","affiliation":[{"name":"University of New South Wales  Sydney New South Wales Australia"},{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Kotlyar","sequence":"additional","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith","family":"Fay","sequence":"additional","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavitha","family":"Muthiah","sequence":"additional","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"},{"name":"University of New South Wales  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nada","family":"Hamad","sequence":"additional","affiliation":[{"name":"University of New South Wales  Sydney New South Wales Australia"},{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Dodds","sequence":"additional","affiliation":[{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikki","family":"Bart","sequence":"additional","affiliation":[{"name":"The Victor Chang Cardiac Research Institute  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Keogh","sequence":"additional","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"},{"name":"The Victor Chang Cardiac Research Institute  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Hayward","sequence":"additional","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"},{"name":"University of New South Wales  Sydney New South Wales Australia"},{"name":"The Victor Chang Cardiac Research Institute  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Macdonald","sequence":"additional","affiliation":[{"name":"Cardiology Department St. Vincent's Hospital  Sydney New South Wales Australia"},{"name":"University of New South Wales  Sydney New South Wales Australia"},{"name":"The Victor Chang Cardiac Research Institute  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Moore","sequence":"additional","affiliation":[{"name":"University of New South Wales  Sydney New South Wales Australia"},{"name":"Department of Haematology and Bone Marrow Transplant St. Vincent's Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,20]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.843334"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13025"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199704243361702"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-02-076034"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2013.095463"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2014.104109"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.8220"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.01285"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019000834"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.7614"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.5724"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2012.09080.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-12-473066"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2018.1485914"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2028631"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.15926","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/imj.15926","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.15926","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T02:39:02Z","timestamp":1692671942000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.15926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/imj.15926"],"URL":"https:\/\/doi.org\/10.1111\/imj.15926","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"value":"1444-0903","type":"print"},{"value":"1445-5994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"2022-01-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}