{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:04:01Z","timestamp":1790298241227,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T00:00:00Z","timestamp":1664755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>The 30\u2010day hospital readmission rate in cirrhotic patients has been demonstrated to be up to 40% in international studies, but is not well studied in Australia. The aim of the current study was to report on the rate and cause of 30\u2010day hospital readmission from a single liver transplant referral centre, including a cost analysis of readmissions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective study of consecutive cirrhotic patients admitted to a liver transplant centre in Victoria, Australia, between 1 January 2019 and 31 December 2019. Cases were identified through<jats:italic>International Classification of Diseases<\/jats:italic>,<jats:italic>Tenth Revision<\/jats:italic>, 10 coding for cirrhosis and its complications. Baseline demographic data, liver\u2010related complications and unrelated extra\u2010hepatic comorbidities, laboratory values and prognostic scores were collected from the electronic medical record.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred seventy\u2010nine (63% men; median age at index admission, 59\u2009years) patients who were admitted 427 times during the study period were included in the final analysis. The 30\u2010day hospital readmission rate was 46%, with the majority of readmissions attributable to fluid overload (29%), miscellaneous reasons (27%) and infection (20%). One fifth of readmissions were considered preventable. History of variceal haemorrhage was found to be an independent predictor of 30\u2010day hospital readmission. The annual cost of readmission is over AU$2.7 million and the median cost of hospital readmission was about AU$9000.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The 30\u2010day hospital readmission rate of 46% is higher than previously reported and almost half of cases were caused by either fluid overload or infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.15932","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T04:03:14Z","timestamp":1663387394000},"page":"2086-2095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Rate of early hospital readmission amongst cirrhotic patients is high in Australia: experience from a single liver transplant centre"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6427-6140","authenticated-orcid":false,"given":"Karl","family":"Vaz","sequence":"first","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Tan","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Chew","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Crawford","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Ma","sequence":"additional","affiliation":[{"name":"Clinical Costing Austin Health Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephine","family":"Grace","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"},{"name":"Department of Medicine The University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Gow","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"},{"name":"Department of Medicine The University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"},{"name":"Department of Medicine The University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Testro","sequence":"additional","affiliation":[{"name":"Victorian Liver Transplant Unit Austin Health Melbourne Victoria Australia"},{"name":"Department of Medicine The University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2005.10.013"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1504367"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.10.035"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.314"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.04.009"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28414"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2019.05.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.1997"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.05.004"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31884"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-1762"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1137"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2019.01.005"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15153"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000050"},{"key":"e_1_2_7_18_1","unstructured":"Centers for Medicare and Medicaid Services.Hospital Readmissions Reduction Program (HRRP). 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