{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:05:50Z","timestamp":1775145950103,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T00:00:00Z","timestamp":1692489600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>There is a growing interest in the appropriate evaluation of penicillin adverse drug reaction (ADR) labels. We have developed machine learning models for classifying penicillin ADR labels using free\u2010text reaction descriptions, and here report external and practical validation. The models performed comparably with expert criteria for the categorisation of allergy or intolerance and identification of high\u2010risk allergies. These models have practical applications in detecting individuals suitable for penicillin ADR evaluation. Implementation studies are required.<\/jats:p>","DOI":"10.1111\/imj.16194","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T05:11:39Z","timestamp":1692681099000},"page":"1485-1488","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Machine learning models automate classification of penicillin adverse drug reaction labels"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0486-9013","authenticated-orcid":false,"given":"Joshua M.","family":"Inglis","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacology Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"},{"name":"Department of Clinical Pharmacology Flinders University and Flinders Medical Centre  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Bacchi","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Troelnikov","sequence":"additional","affiliation":[{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"},{"name":"Clinical Immunology &amp; Allergy Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Flinders University  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Smith","sequence":"additional","affiliation":[{"name":"Adelaide Medical School, Faculty of Health and Medical Sciences University of Adelaide  Adelaide South Australia Australia"},{"name":"Clinical Immunology &amp; Allergy Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepehr","family":"Shakib","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Pharmacology School of Medicine, University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix794"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2017.09.012"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw462"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa653"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.09.025"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.02.046"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.024124"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2021.104611"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13558"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.15209"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.43_13197"},{"key":"e_1_2_5_13_1","unstructured":"ASCIA Drug Allergy Working Party.ASCIA Consensus Statement for the Assessment of Patients with Immediate (IgE Mediated) Penicillin Allergy. 2016."},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2018.07.048"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13042-010-0001-0"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13601-019-0259-6"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:MACH.0000011806.12374.c3"},{"key":"e_1_2_5_18_1","doi-asserted-by":"crossref","unstructured":"KuoNIH HarandiM FourrierN WalderC FerraroG SuominenH.Plastic and stable gated classifiers for continual learning. 2021 IEEE\/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW); 2021; 3548\u20133553.","DOI":"10.1109\/CVPRW53098.2021.00394"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.16194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T12:43:04Z","timestamp":1752756184000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.16194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1111\/imj.16194"],"URL":"https:\/\/doi.org\/10.1111\/imj.16194","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"value":"1444-0903","type":"print"},{"value":"1445-5994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"2022-09-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}