{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T12:09:24Z","timestamp":1785326964615,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anticoagulation can prevent most strokes in individuals with atrial fibrillation (AF); however, many people presenting with stroke and known AF are not anticoagulated. Language barriers and poor health literacy have previously been associated with decreased patient medication adherence. The association between language barriers and initiation of anticoagulation therapy for AF is uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The aims of this study were to determine whether demographic factors, including non\u2010English primary language, were (1) associated with not being initiated on anticoagulation for known AF prior to admission with stroke, and (2) associated with non\u2010adherence to anticoagulation in the setting of known AF prior to admission with stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multicentre retrospective cohort study was conducted for consecutive individuals admitted to the three South Australian tertiary hospitals with stroke units over a 5\u2010year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 6829 individuals admitted with stroke. These cases included 5835 ischaemic stroke patients, 1333 of whom had pre\u2010existing AF. Only 40.0% presenting with ischaemic stroke in the setting of known pre\u2010existing AF were anticoagulated. When controlling for demographics, socioeconomic status and past medical history (including the components of the CHADS2VASC score and anticoagulation contraindications), having a primary language other than English was associated with a lower likelihood of having been commenced on anticoagulant for known pre\u2010stroke AF (odds ratio: 0.52, 95% confidence interval: 0.36\u20130.77,\n                      <jats:italic>P<\/jats:italic>\n                      =\u20090.001), but was not associated with a differing likelihood of anticoagulation adherence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A significant proportion of patients with stroke have pre\u2010existing unanticoagulated AF; these rates are substantially higher if the primary language is other than English. Targeted research and interventions to minimise evidence\u2010treatment gaps in this cohort may significantly reduce stroke burden.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/imj.16253","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T06:12:08Z","timestamp":1697782328000},"page":"620-625","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pre\u2010stroke anticoagulation for atrial fibrillation in primary English speakers and non\u2010primary English speakers: a multicentre retrospective cohort study"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5130-8628","authenticated-orcid":false,"given":"Stephen","family":"Bacchi","sequence":"first","affiliation":[{"name":"College of Medicine and Public Health, Flinders University  Adelaide South Australia Australia"},{"name":"University of Adelaide  Adelaide South Australia Australia"},{"name":"Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua G.","family":"Kovoor","sequence":"additional","affiliation":[{"name":"University of Adelaide  Adelaide South Australia Australia"},{"name":"Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy","family":"Goh","sequence":"additional","affiliation":[{"name":"University of Adelaide  Adelaide South Australia Australia"},{"name":"Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Lyell McEwin Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashray K.","family":"Gupta","sequence":"additional","affiliation":[{"name":"University of Adelaide  Adelaide South Australia Australia"},{"name":"Gold Coast University Hospital  Gold Coast Queensland 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