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We present a case of a 60\u2010year\u2010old woman with acute heart failure, DRESS syndrome features and human herpesvirus 6 reactivation in the absence of a drug trigger. She was diagnosed with eosinophilic myocarditis and successfully treated with corticosteroid therapy.<\/jats:p>","DOI":"10.1111\/imj.16346","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T13:05:29Z","timestamp":1708520729000},"page":"499-502","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>DRESS<\/scp> syndrome with multiorgan involvement and <scp>HHV\u20106<\/scp> reactivation in the absence of a drug trigger"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3036-7391","authenticated-orcid":false,"given":"Yi Tong Vincent","family":"Aw","sequence":"first","affiliation":[{"name":"Department of General Medicine Canberra Hospital, Canberra Health Services  Canberra Australian Capital Territory Australia"},{"name":"ANU Medical School, School of Medicine and Psychology Australian National University  Canberra Australian Capital Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meidelynn","family":"Ooi","sequence":"additional","affiliation":[{"name":"Division of Medicine Canberra Hospital, Canberra Health Services  Canberra Australian Capital Territory Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel","family":"Ekladious","sequence":"additional","affiliation":[{"name":"Department of General Medicine Canberra Hospital, Canberra Health Services  Canberra Australian Capital Territory Australia"},{"name":"Acute Medical Unit Canberra Hospital, Canberra Health Services  Canberra Australian Capital Territory Australia"},{"name":"Faculty of Health and Medical Sciences University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,21]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2011.01.017"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11030704"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.11.057"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-1352"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/v14020299"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-018-3273-1"},{"key":"e_1_2_4_8_1","first-page":"3","article-title":"Cardiac involvement in DRESS syndrome","volume":"35","author":"Thongsri T","year":"2017","journal-title":"Asian Pac J Allergy Immunol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-242240"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.14450"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.909569"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14956"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12501"},{"key":"e_1_2_4_14_1","article-title":"The clinicopathological profile of eosinophilic myocarditis","volume":"10","author":"Sheikh H","year":"2018","journal-title":"Cureus"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12144576"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7863815"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.55563\/clinexprheumatol\/styx9u"},{"key":"e_1_2_4_18_1","first-page":"1","article-title":"An uncommon presentation of DRESS syndrome secondary to Leflunomide use: a case report","volume":"9","author":"Rao S","year":"2021","journal-title":"J Investig Med High Impact Case Rep"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1733"},{"key":"#cr-split#-e_1_2_4_20_1.1","unstructured":"ZaarouraH ShearNH.Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). McMaster Textbook of Internal Medicine. Krak\u00f3w: Medycyna Praktyczna. [Updated 2021 Jul 26"},{"key":"#cr-split#-e_1_2_4_20_1.2","unstructured":"Cited 2023 Nov 28]. Available from URL:https:\/\/empendium.com\/mcmtextbook\/chapter\/B31.II.856.7"},{"key":"#cr-split#-e_1_2_4_21_1.1","unstructured":"RamnaniD.Eosinophilic Myocarditis. Webpathology [Updated 2023 Dec 9"},{"key":"#cr-split#-e_1_2_4_21_1.2","unstructured":"Cited 2023 Nov 28]. Available from URL:https:\/\/www.webpathology.com\/image.asp?n=3&Case=514"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.16346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T05:32:46Z","timestamp":1710307966000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.16346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,21]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/imj.16346"],"URL":"https:\/\/doi.org\/10.1111\/imj.16346","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"type":"print","value":"1444-0903"},{"type":"electronic","value":"1445-5994"}],"subject":[],"published":{"date-parts":[[2024,2,21]]},"assertion":[{"value":"2023-09-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}