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We used omalizumab, an anti\u2010immunoglobulin E antibody, to overcome immediate and delayed hypersensitivity reactions to various anticancer drugs. Seven of the eight patients in the current study\u00a0successfully resumed the desired anticancer\u00a0drug regimen without standard desensitisation. No safety issues from omalizumab were observed.<\/jats:p>","DOI":"10.1111\/imj.16464","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T09:03:52Z","timestamp":1721379832000},"page":"1396-1400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Omalizumab for management of hypersensitivity reactions to anticancer drugs"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5717-6507","authenticated-orcid":false,"given":"Piyush","family":"Grover","sequence":"first","affiliation":[{"name":"Department of Immunology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"Medical School, The University of Western Australia  Perth Western Australia Australia"},{"name":"Department of Medical Oncology Fiona Stanley Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Krummenacher","sequence":"additional","affiliation":[{"name":"Department of Immunology Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Loy","sequence":"additional","affiliation":[{"name":"Department of Immunology Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna K.","family":"Nowak","sequence":"additional","affiliation":[{"name":"Medical School, The University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Lucas","sequence":"additional","affiliation":[{"name":"Department of Immunology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"Medical School, The University of Western Australia  Perth Western Australia Australia"},{"name":"Department of Immunology Perth Children's Hospital  Perth Western Australia Australia"},{"name":"PathWest  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11702"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2020.08.006"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.02.044"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.18176\/jiaci.0425"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2015.12.019"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215372"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2013.08.009"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.18176\/jiaci.0326"},{"key":"e_1_2_3_11_1","unstructured":"5 CTCAE.US Department of Health and Human Services National Institutes of Health National Cancer Institute; 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