{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T04:32:34Z","timestamp":1696998754648},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,9,14]],"date-time":"2017-09-14T00:00:00Z","timestamp":1505347200000},"content-version":"vor","delay-in-days":20955,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Australasian Annals of Medicine"],"published-print":{"date-parts":[[1960,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Attention is drawn to a complement\u2010fixing agent which reacts with extract of normal thyroid gland. There are reasons for regarding this agent as an antibody, and possibly as an auto\u2010antibody. It is significantly associated with thyroid disease, though not so closely as the complement\u2010fixing anti\u2010thyrotoxic antibody, or the anti\u2010thyroglobulin antibody which reacts in the tanned\u2010cell h\u00e6magglutination technique. It is also associated with some other types of disease, particularly syphilis, the \u201ccollagen disease\u201d group, and viral infections. In non\u2010thyroid diseases, positive reactors are almost equally distributed between the sexes.<\/jats:p><jats:p>Any attempted synthesis of the current knowledge of the association between thyroid disease and the presence of serum auto\u2010antibodies should take this agent into account, even though its activity or significance <jats:italic>in vivo<\/jats:italic> may be not entirely confined to the thyroid gland and its functions.<\/jats:p>","DOI":"10.1111\/imj.1960.9.2.93","type":"journal-article","created":{"date-parts":[[2017,9,14]],"date-time":"2017-09-14T13:40:09Z","timestamp":1505396409000},"page":"93-98","source":"Crossref","is-referenced-by-count":3,"title":["COMPLEMENT FIXATION WITH EXTRACT OF NORMAL THYROID GLAND : ITS OCCURRENCE IN SERA FROM PATIENTS WITH THYROID DISEASE AND IN OTHER CONDITIONS"],"prefix":"10.1111","volume":"9","author":[{"given":"EARLE","family":"HACKETT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARGARET","family":"BEECH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IAN J.","family":"FORBES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(59)92400-6"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.93.2.107"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5153.645"},{"key":"e_1_2_1_5_1","volume-title":"Proceedings of the 1st International Symposium on Immunopathology, Basel\/Seelisberg, 1958","author":"CRUICKSHANK B.","year":"1959"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(48)90061-4"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400019732"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/179666a0"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1958.00260130023003"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700770208"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","unstructured":"HACKETT E. 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(1960) \u201cThyroglobulin Antibodies in Patients without Clinical Disease of the Thyroid Gland\u201d Lancet in the press.","DOI":"10.1016\/S0140-6736(60)92842-7"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1958.00260130044004"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.84.6.535"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(58)90530-0"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.08.020157.001323"}],"container-title":["Australasian Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fimj.1960.9.2.93","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.1960.9.2.93","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T23:43:08Z","timestamp":1696981388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.1960.9.2.93"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1960,5]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1960,5]]}},"alternative-id":["10.1111\/imj.1960.9.2.93"],"URL":"https:\/\/doi.org\/10.1111\/imj.1960.9.2.93","archive":["Portico"],"relation":{},"ISSN":["0571-9283"],"issn-type":[{"value":"0571-9283","type":"print"}],"subject":[],"published":{"date-parts":[[1960,5]]}}}