{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T10:53:43Z","timestamp":1699700023446},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,14]],"date-time":"2017-09-14T00:00:00Z","timestamp":1505347200000},"content-version":"vor","delay-in-days":20498,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Australasian Annals of Medicine"],"published-print":{"date-parts":[[1961,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The clinical features and autopsy findings are described in two cases of pancytopenia, four cases of leuk\u00e6mia and one case of myelofibrosis, all of which were associated with disseminated tuberculosis.<\/jats:p><jats:p>It is considered that tuberculosis preceded and may have caused pancytopenia in three cases. Diagnosis in such cases is aided by biopsy of lymph glands, liver and bone marrow from the iliac crest, and by culture of biopsy material. The pancytopenia should respond to anti\u2010tuberculous chemotherapy, but in one case it progressed to leuk\u00e6mia despite treatment.<\/jats:p><jats:p>Tuberculosis appeared as a complication in three cases of leuk\u00e6mia and in one case of myelofibrosis. These cases pursue their natural course despite anti\u2010tuberculous chemotherapy. Tuberculosis seems more likely to occur in patients receiving cortisone.<\/jats:p><jats:p>We consider that \u201c leuk\u00e6moid reaction \u201d to tuberculosis is not common, and that, more commonly, leuk\u00e6mia is complicated by tuberculosis. In a few cases tuberculosis may be an \u00e6tiological factor in the blood dyscrasia, most commonly in cases of pancytopenia.<\/jats:p>","DOI":"10.1111\/imj.1961.10.3.230","type":"journal-article","created":{"date-parts":[[2017,9,14]],"date-time":"2017-09-14T07:12:35Z","timestamp":1505373155000},"page":"230-236","source":"Crossref","is-referenced-by-count":5,"title":["DISSEMINATED TUBERCULOSIS AND BONE MARROW DYSCRASIAS"],"prefix":"10.1111","volume":"10","author":[{"given":"J. K.","family":"DAWBORN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. C.","family":"COWLING","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4736.869"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5212.1552"},{"key":"e_1_2_1_4_1","first-page":"165","article-title":"The Anemia of Infection, a Review","volume":"5","author":"CARTWRIGHT G. E.","year":"1952","journal-title":"Adv. intern. Med."},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1182\/blood.V3.12.1426.1426","article-title":"Miliary Tuberculosis and Myelofibrosis","volume":"3","author":"CRAIL H. W.","year":"1948","journal-title":"Blood"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(50)91344-4"},{"key":"e_1_2_1_7_1","first-page":"383","volume-title":"Clinical H\u00e6matology in Medical Practice","author":"DE GRUCHY G. C.","year":"1958"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193801000-00006"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193701000-00005"},{"key":"e_1_2_1_10_1","first-page":"187","article-title":"Leuk\u00e6mia and Allied Disorders","author":"FORKNER C. E.","year":"1938","journal-title":"Macmillan, New York"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1182\/blood.V4.6.767.767","article-title":"Lymphocytic Leuk\u00e6moid Reaction of the Blood Associated with Miliary Tuberculosis","volume":"4","author":"GARDINER F. H.","year":"1949","journal-title":"Blood"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700580317"},{"key":"e_1_2_1_13_1","first-page":"145","article-title":"Polycythemia Vera with Tuberculous Splenomegaly","volume":"57","author":"GUILD A. A.","year":"1950","journal-title":"Edinb. med. J."},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.12.4.307"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1960.tb17381.x"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4675.399-a"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5163.1375"},{"key":"e_1_2_1_18_1","first-page":"351","article-title":"Tuberculous Miliary Necrosis with Pancytopenia","volume":"24","author":"MEDD W. E.","year":"1955","journal-title":"Quart. J. Med."},{"key":"e_1_2_1_19_1","first-page":"737","volume-title":"The Principles and Practice of Medicine","author":"OSLER W.","year":"1907"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)82115-7"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0366-0869(56)80005-1"},{"key":"e_1_2_1_22_1","first-page":"709","article-title":"Studies in Leuk\u00e6mia. III. Agglutination of Human Leukaemic Cells by Guinea Pig Serum","volume":"46","author":"SCHWARTZ S. O.","year":"1955","journal-title":"J. Lab. clin. Med."},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193801000-00004"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V5.12.1161.1161"},{"key":"e_1_2_1_25_1","first-page":"225","article-title":"La ricerca de metabolismo basale nelle leucemie Croniche quale direttiva alla terapia","volume":"105","author":"VOLPE A.","year":"1896","journal-title":"Bull. Sc. med. (Bologna)"},{"key":"e_1_2_1_26_1","first-page":"481","volume-title":"Disorders of the Blood","author":"WHITBY L. E. H.","year":"1957"}],"container-title":["Australasian Annals of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fimj.1961.10.3.230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.1961.10.3.230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T05:15:03Z","timestamp":1697001303000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.1961.10.3.230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1961,8]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1961,8]]}},"alternative-id":["10.1111\/imj.1961.10.3.230"],"URL":"https:\/\/doi.org\/10.1111\/imj.1961.10.3.230","archive":["Portico"],"relation":{},"ISSN":["0571-9283"],"issn-type":[{"value":"0571-9283","type":"print"}],"subject":[],"published":{"date-parts":[[1961,8]]}}}