{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T04:12:31Z","timestamp":1747282351560,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001063","name":"Raine Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001063","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The relationship between type 2 diabetes and the incidence of transurethral resection of the prostate (TURP) remains uncertain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To utilise data from the Fremantle Diabetes Study Phase I (FDS1) to examine the association between type 2 diabetes and incident TURP and investigate risk factors in men with type 2 diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>First TURP hospitalisations were ascertained for males from the Fremantle Diabetes Study Phase I (<jats:italic>n<\/jats:italic> =\u2009581) and age\u2010 and postcode\u2010matched men without diabetes (<jats:italic>n<\/jats:italic> =\u20092361) between entry (1993\u20131996) and end (2017). Incidence rate ratios (IRRs) were calculated. Cox proportional hazards and competing risk models generated cause\u2010specific (cs) and subdistribution (sd) hazard ratios (HRs) for incident TURP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 86 and 338 TURP hospitalisations in participants with and without type 2 diabetes, respectively, during 42\u2009236 person\u2010years of follow\u2010up. The IRR (95% confidence interval) for diabetes versus no diabetes was 1.23 (0.96, 1.56). A 10\u2010year age increase more than doubled the risk of incident TURP (csHR 2.51 (2.02, 3.12), sdHR 2.59 (2.11, 3.18)), but type 2 diabetes was not a significant predictor in multivariable models. In participants with type 2 diabetes, a 10\u2010year age increase was predictive (csHR 2.94 (1.93, 4.47), sdHR 1.92 (1.51, 2.44)); Anglo\u2010Celt versus other ethnic groups was significant in the Cox (csHR 1.87 (1.17, 3.00)) but not competing risk (sdHR 1.60 (0.99, 2.57)) models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Type 2 diabetes does not increase TURP risk in community\u2010based Australians. There are no diabetes\u2010specific variables associated with incident TURP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.70021","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T01:03:34Z","timestamp":1741741414000},"page":"760-766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence and predictors of transurethral resection of prostate in men with and without type 2 diabetes: the Fremantle Diabetes Study Phase I"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0749-7411","authenticated-orcid":false,"given":"Timothy M. E.","family":"Davis","sequence":"first","affiliation":[{"name":"Medical School The University of Western Australia, Fremantle Hospital  Fremantle Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5709-8235","authenticated-orcid":false,"given":"Wendy A.","family":"Davis","sequence":"additional","affiliation":[{"name":"Medical School The University of Western Australia, Fremantle Hospital  Fremantle Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.1997.tb00138.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-013737"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2015.301"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.741748"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.05.021"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2490-13-12"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpha.2023.08.012"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0219394"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/jomh.2014.0051"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-041875"},{"key":"e_1_2_7_12_1","unstructured":"Australian Diabetes Society.Australian Blood Glucose Treatment Algorithm for Type 2 Diabetes.2025[cited 2025 Jan].https:\/\/treatment.diabetessociety.com.au\/plan\/."},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys065"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-0053"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9241904"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.03.06.dc05-1567"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-842X.1999.tb01297.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000506717"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2017.02.005"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2022.0654"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-022-04179-w"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.31128\/AFP-08-17-4292"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40615-023-01538-0"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-022-01118-5"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.07.059"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.70021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T16:05:07Z","timestamp":1747238707000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.70021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,10]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/imj.70021"],"URL":"https:\/\/doi.org\/10.1111\/imj.70021","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"type":"print","value":"1444-0903"},{"type":"electronic","value":"1445-5994"}],"subject":[],"published":{"date-parts":[[2025,3,10]]},"assertion":[{"value":"2025-01-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}