{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T04:13:00Z","timestamp":1749701580616,"version":"3.41.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The prevention of mother\u2010to\u2010child transmission of hepatitis B virus (HBV) is essential to achieve the World Health Organization's goal of eliminating HBV as a public health threat by 2030. This study examines the management of HBV in pregnant women and newborns at a large tertiary health service in Victoria, Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate the timely administration of hepatitis B immune globulin (HBIG) and the birth dose vaccine to infants born to mothers with chronic hepatitis B (CHB) and to assess maternal referral to specialist care, viral load (VL) testing and antiviral therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study reviewed medical records of women with CHB who delivered at Monash Health from 2014 to 2022. Data were extracted on maternal referral to specialist care, VL testing, antiviral use and administration timing of HBIG (within 12 h) and hepatitis B vaccine (within 24 h) to newborns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 895 infants, 99.7% received both HBIG and the birth dose vaccine; 97.4% received the vaccine within 12 h, and 88.3% received HBIG within the recommended 12\u2010h window. Maternal referral rates to specialist care were 83.1%, with 91.06% undergoing VL testing during pregnancy. Antiviral therapy was administered to 16% of women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>High uptake of HBV immunoprophylaxis was observed, with most infants receiving timely vaccination and HBIG. However, variability exists in maternal referral and antiviral treatment. Continued efforts are needed to improve comprehensive care and reduce transmission risk across diverse settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.70048","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T11:56:27Z","timestamp":1743508587000},"page":"932-936","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Audit of linkage to care and administration of immunoprophylaxis to infants born to mothers with chronic hepatitis B infection at Monash Health 2014\u20132022"],"prefix":"10.1111","volume":"55","author":[{"given":"Cian","family":"Lenihan","sequence":"first","affiliation":[{"name":"South East Public Health Unit Monash Health  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3918-0091","authenticated-orcid":false,"given":"Anna B.","family":"Pierce","sequence":"additional","affiliation":[{"name":"South East Public Health Unit Monash Health  Melbourne Victoria Australia"},{"name":"Monash Infectious Diseases Monash Health  Melbourne Victoria Australia"},{"name":"Faculty of Medicine, Nursing and Health Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edura","family":"Jalil","sequence":"additional","affiliation":[{"name":"South East Public Health Unit Monash Health  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3487-7244","authenticated-orcid":false,"given":"Rhonda L.","family":"Stuart","sequence":"additional","affiliation":[{"name":"South East Public Health Unit Monash Health  Melbourne Victoria Australia"},{"name":"Faculty of Medicine, Nursing and Health Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Australian Government Department of Health and Aged Care.Fourth national hepatitis b strategy 2023\u20132030[cited 2024 Sept 30]. Available from URL:https:\/\/www.health.gov.au\/sites\/default\/files\/2023-05\/fourth-national-hepatitis-b-strategy-2023-2030.pdf"},{"volume-title":"Australian Immunisation Handbook","year":"2022","author":"Australian Technical Advisory Group on Immunisation (ATAGI)","key":"e_1_2_7_3_1"},{"key":"e_1_2_7_4_1","unstructured":"Troung A Walker S.Management of hepatitis B in pregnancy: the Royal Australian and New Zealand College of Obstetricians and Gynaecologists;2019[cited 2024 Sept 30]. Available from URL:https:\/\/ranzcog.edu.au\/wp-content\/uploads\/2022\/05\/Management-of-Hepatitis-B-in-pregnancy-C-Obs-50.pdf"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2023.01.045"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.16711"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1071\/PY22158"},{"key":"e_1_2_7_8_1","unstructured":"Victorian Department of Health.Specifications for revisions to the VPDC for 1 July 2023[cited 2025 Feb 21]. Available from URL:https:\/\/www.health.vic.gov.au\/quality-safety-service\/vpdc-archive"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13466"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X17731990"},{"key":"e_1_2_7_11_1","unstructured":"Maclachlan JH Romero N Purcell I Cowie BC.Viral hepatitis mapping project: hepatitis B national report 2022;2024[cited 2025 Feb 21]. Available from URL:https:\/\/ashm.org.au\/resources\/viral-hepatitis-mapping-project\/"},{"key":"e_1_2_7_12_1","unstructured":"NSW Health.Neonatal and infant hepatitis B prevention and vaccination program policy directive;2023[cited 2024 Sept 30]. Available from URL:https:\/\/www1.health.nsw.gov.au\/pds\/ActivePDSDocuments\/PD2023_032.pdf"}],"container-title":["Internal Medicine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imj.70048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T16:04:57Z","timestamp":1749657897000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imj.70048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/imj.70048"],"URL":"https:\/\/doi.org\/10.1111\/imj.70048","archive":["Portico"],"relation":{},"ISSN":["1444-0903","1445-5994"],"issn-type":[{"type":"print","value":"1444-0903"},{"type":"electronic","value":"1445-5994"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}