{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:41:48Z","timestamp":1785516108992,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Low adherence rates in addition to inhaler misuse is a crucial problem in asthma management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate medication adherence and correct inhaler use and the relationship between adherence, asthma control and disease severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional study, demographic characteristics of patients with asthma, asthma control and severe asthma rates were recorded. Patients were categorised as non\u2010adherent, adherent to one component (either subjectively or objectively adherent), adherent to two components or full adherent based on objective, subjective and correct inhaler device use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 304 patients with a mean age of 50.21 \u00b1\u200912.53\u2009years and disease duration of 12.67 \u00b1\u20099.47\u2009years. The rate of objective adherence, subjective adherence and correct inhaler use was 45.3%, 67.7% and 56.5% respectively. Overall, we found that 26% of the patients were non\u2010adherent, 18.7% showed subjective or objective adherence, 28.8% adhered to two components, and 27% demonstrated full adherence. The risk of non\u2010adherence was 3.1 times higher in uncontrolled patients, and regular clinician visits reduced the risk of non\u2010adherence by 66%. Adherence was negatively associated with severe asthma rates in our cohort. The rate of correct inhaler device use was lower in patients with systemic comorbidities, while there was no difference in objective adherence, subjective adherence or full adherence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study revealed that correct, consistent and regular use of inhalers in accordance with clinician recommendations is important in achieving control in patients with asthma. To increase adherence in asthma, regular clinician visits and repeat training should be encouraged.<\/jats:p><\/jats:sec>","DOI":"10.1111\/imj.70135","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T05:21:38Z","timestamp":1751347298000},"page":"1483-1490","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of adherence on asthma control: more patient knowledge, more adherence, more control"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4188-0959","authenticated-orcid":false,"given":"Zeynep","family":"Celebi Sozener","sequence":"first","affiliation":[{"name":"Department of Chest Diseases, Division of Immunology and Allergic Diseases Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omur","family":"Aydin","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Division of Immunology and Allergic Diseases Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulfem Elif","family":"Celik","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Division of Immunology and Allergic Diseases Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilsad","family":"Mungan","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Division of Immunology and Allergic Diseases Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"GINA.Global Strategy for Asthma Management and Prevention 2023. Available from URL:www.ginasthma.org.2023."},{"key":"e_1_2_6_3_1","unstructured":"Ast\u0131m Tan\u0131 ve Tedavi Rehberi 2020 G\u00fcncellemesi.2020. Available from URL:https:\/\/www.toraks.org.tr."},{"key":"e_1_2_6_4_1","volume-title":"Adherence to Long\u2010Term Therapies: Evidence for Action","author":"Organization WH","year":"2003"},{"key":"e_1_2_6_5_1","unstructured":"Global Initiative for Asthma.Global Strategy for Asthma Management and Prevention2020Available from URL:www.ginasthma.org."},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-20-2360"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0176-2021"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.5603\/ARM.2019.0036"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40733-022-00083-7"},{"key":"e_1_2_6_10_1","first-page":"113","article-title":"Risk factors for poor adherence to inhaled corticosteroid therapy in patients with moderate to severe asthma","volume":"41","author":"Masaki K","year":"2023","journal-title":"Asian Pac J Allergy Immunol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201908-1590ST"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/02770903.2013.871558"},{"key":"e_1_2_6_13_1","unstructured":"Inhaler Standards and Competency Document.2021. 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