{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T15:14:55Z","timestamp":1762960495649,"version":"3.45.0"},"reference-count":37,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Haematology inpatients are at high risk of acute deterioration. This study aimed to examine the frequency, characteristics and outcomes of medical emergency team (MET) activations in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was conducted of all haematology admissions to a tertiary hospital over 2\u2009years. The primary outcome was the frequency of MET activation during an inpatient haematology admission. Secondary outcomes included identifying factors associated with MET calls and evaluating their relationship with in\u2010hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the study period, there were 485 MET activations. Of the 1682 admissions in the study period, 278 admissions (17%) were complicated by MET activation. Of the 757 patients admitted in the study period, 223 patients (29%) had a MET activation. Acute myeloid leukaemia, higher Charlson Comorbidity Index scores and allogeneic stem cell transplantation were more common in patients who had a MET call. Nearly one\u2010third of MET activations occurred within 48 h of admission. Common triggers were tachypnoea, tachycardia and hypotension. Intensive care unit (ICU) admission was more frequent with MET activation (24% vs. 3%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001), as were longer median hospital stays (15.4 vs. 5.1\u2009days,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001) and higher in\u2010hospital mortality (14% vs. 1%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001). Repeated MET calls increased the likelihood of ICU transfer. MET activation was strongly associated with in\u2010hospital mortality (odds ratio, 37.87;\u00a095% confidence interval, 10.98\u2013130.58).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MET activation occurs in nearly one in five haematology admissions and is associated with an increased risk of morbidity and mortality. Patients with acute myeloid leukaemia, high comorbidity or post\u2010allogeneic transplant status are at the greatest risk, supporting the need for targeted monitoring and preventative strategies in this high\u2010risk group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/imj.70230","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T11:25:54Z","timestamp":1761391554000},"page":"1917-1927","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antecedents to and outcomes of medical emergency team calls in haematology patients"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9343-542X","authenticated-orcid":false,"given":"Abbey","family":"Willcox","sequence":"first","affiliation":[{"name":"Department of Clinical Haematology Alfred Health  Melbourne Victoria Australia"},{"name":"Department of Haematology Austin Hospital  Melbourne Victoria Australia"},{"name":"The Australian Centre for Blood Diseases Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Haematology Austin Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"See","sequence":"additional","affiliation":[{"name":"Department of Critical Care University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Intensive Care The Royal Melbourne Hospital  Melbourne Victoria Australia"},{"name":"Department of Intensive Care Austin Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew Boon Ming","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Haematology Austin Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daryl","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Austin Hospital  Melbourne Victoria Australia"},{"name":"Department of Epidemiology and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0910926"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000235743.38172.6E"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.424"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4263-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-0973-y"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhm.2554"},{"key":"e_1_2_7_8_1","first-page":"275","article-title":"Resource use, governance and case load of rapid response teams in Australia and New Zealand in 2014","volume":"18","author":"Joint College of Intensive Care Medicine and Australian and New Zealand Intensive Care Society Special Interest Group on Rapid Response Systems","year":"2016","journal-title":"Crit Care Resusc"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e3283636be2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11061736"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2013.773996"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161401"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2021.1966223"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000119428.02968.9E"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2003.tb05548.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2006.01045.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31822e9d50"},{"key":"e_1_2_7_18_1","unstructured":"World Health Organization.International statistical classification of diseases and related health problems (10th rev. 5th ed.).2019[cited 2025 Aug 10]. 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