{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T17:14:10Z","timestamp":1778087650270,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Alcohol\u2010associated hepatitis (AAH) causes significant morbidity, mortality and healthcare expenditure. Increased alcohol consumption during the SARS\u2010CoV\u20102 (COVID\u201019) pandemic was observed globally.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to assess temporal associations between the COVID\u201019 pandemic and AAH admission frequency and outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study of inpatients aged \u226518\u2009years fulfilling National Institute of Alcohol Abuse and Alcoholism diagnostic criteria for AAH from three Australian tertiary referral hospitals. AAH admissions and outcomes between 1 March 2020 and 31 March 2021 (\u2018COVID\u201019 cohort\u2019) were compared with a \u2018historical cohort\u2019 (1 January 2016\u201329 February 2020). The primary endpoint was the monthly rate of AAH admissions according to the COVID\u201019 timepoint. Secondary outcomes included change in AAH severity, interventions and healthcare costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the study period, 301 eligible AAH admissions were identified. The COVID\u201019 cohort (\n                      <jats:italic>n<\/jats:italic>\n                      =\u2009104) had a significantly higher median AAH monthly admission rate (8 (interquartile range (IQR) 6, 9) vs 3 (3, 5),\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.0001) and proportion requiring intensive care unit admission (26% (\n                      <jats:italic>n<\/jats:italic>\n                      =\u200927) vs 12% (\n                      <jats:italic>n<\/jats:italic>\n                      =\u200924),\n                      <jats:italic>P<\/jats:italic>\n                      =\u20090.002), despite similar median MELD\u2010Na scores (20 (IQR 15, 25.5) vs 19 (14, 25),\n                      <jats:italic>P<\/jats:italic>\n                      =\u20090.24) to the historical cohort (\n                      <jats:italic>n<\/jats:italic>\n                      =\u2009197). Higher median monthly healthcare costs were identified in the COVID\u201019 cohort ($90\u2009912 (IQR 43 853, 243 469) vs $42\u2009983 (IQR 18 231, 71 410),\n                      <jats:italic>P<\/jats:italic>\n                      =\u20090.03). Ninety\u2010day mortality was 14%. No patients were diagnosed with COVID\u201019.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this multicentre analysis, AAH admission frequency, ICU requirement and healthcare costs increased during the COVID\u201019 pandemic. These observations provide the impetus for future studies to help develop preventive strategies that reduce alcohol\u2010related admissions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/imj.70389","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:59:35Z","timestamp":1772967575000},"page":"573-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Accelerated impact of alcohol\u2010associated hepatitis on healthcare utilisation during the\n                    <scp>COVID<\/scp>\n                    \u201019 pandemic"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1170-2828","authenticated-orcid":false,"given":"Leya","family":"Nedumannil","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Austin Health  Heidelberg Victoria 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