{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T14:16:19Z","timestamp":1788617779997,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:00:00Z","timestamp":1788566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:00:00Z","timestamp":1788566400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with ST\u2010segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) are at heightened risk of acute kidney injury (AKI). Prior studies have suggested that serum N\u2010terminal pro\u2010B\u2010type natriuretic peptide (NT\u2010proBNP) may be linked to AKI development, proposing it as a potential predictive biomarker.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aimed to evaluate whether changes in NT\u2010proBNP levels are associated with the risk of AKI in STEMI patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective analysis included 107 STEMI patients who underwent PCI. Patients were stratified into three groups based on the percentage change in NT\u2010proBNP levels: a reduction &gt;\u200930%, a reduction \u2264\u200930%, or an increase. The primary endpoints were post\u2010PCI AKI incidence and 180\u2010day mortality. Logistic regression was used to assess the association between NT\u2010proBNP dynamics and AKI risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A reduction in NT\u2010proBNP of &gt;30% was independently associated with a reduced risk of postoperative AKI (OR\u2009=\u20090.41, 95% CI 0.17\u20130.98,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.045). This group also exhibited the favorable survival profile, with the lowest 180\u2010day mortality rate (11\/62, 17.7%) compared to the \u2264\u200930% reduction group (9\/27, 33.3%) and the increase group (13\/18, 72.2%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 for trend).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dynamics of NT\u2010proBNP levels are closely associated with the incidence of AKI following PCI in STEMI patients. Specifically, an NT\u2010proBNP reduction of &gt;30% may serve as a robust biomarker for predicting lower post\u2010PCI AKI risk and improved short\u2010term survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/imj.70524","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T13:59:50Z","timestamp":1788616790000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of changes in N\u2010terminal pro\u2010B\u2010type natriuretic peptide on the outcome of acute kidney injury in patients with ST\u2010segment elevation myocardial infarction after percutaneous coronary intervention: a retrospective study"],"prefix":"10.1111","author":[{"given":"Chongrong","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Emergency Ganzhou People's Hospital, The Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University  Nanchang 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