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In recent years, key improvements to existing vectors such as those based on adenovirus have led to significant improvements in immunogenicity and efficacy. Furthermore, exciting new vectors that exploit viruses such as cytomegalovirus (<jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>) and vesicular stomatitis virus (<jats:styled-content style=\"fixed-case\">VSV<\/jats:styled-content>) have emerged. Herein, we summarize these recent developments in viral vector technologies, focusing on novel vectors based on <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> VSV<\/jats:styled-content>, measles and modified adenovirus. We discuss the potential utility of these exciting approaches in eliciting protection against infectious diseases.<\/jats:p>","DOI":"10.1111\/imm.12829","type":"journal-article","created":{"date-parts":[[2017,9,4]],"date-time":"2017-09-04T18:36:34Z","timestamp":1504550194000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":139,"title":["Novel viral vectors in infectious diseases"],"prefix":"10.1111","volume":"153","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9512-5337","authenticated-orcid":false,"given":"Ian R.","family":"Humphreys","sequence":"first","affiliation":[{"name":"Institute of Infection and Immunity\/Systems Immunity University Research Institute Cardiff University Cardiff UK"},{"name":"The Wellcome Trust Sanger Institute Hinxton 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