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Here we describe the International Union of Basic and Clinical Pharmacology (IUPHAR) Guide to Immunopharmacology (GtoImmuPdb), which connects expert\u2010curated pharmacology with key immunological concepts and aims to put pharmacological data into the hands of immunologists. In the pursuit of new therapeutics, pharmacological databases are a vital resource to researchers through providing accurate information on the fundamental science underlying drug action. This extension to the existing IUPHAR\/British Pharmacological Society Guide to Pharmacology supports research into the development of drugs targeted at modulating immune, inflammatory or infectious components of disease. To provide a deeper context for how the resource can support research we show data in GtoImmuPdb relating to a case study on the targeting of vascular inflammation.<\/jats:p>","DOI":"10.1111\/imm.13175","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T09:36:25Z","timestamp":1580895385000},"page":"10-23","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology"],"prefix":"10.1111","volume":"160","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9262-8318","authenticated-orcid":false,"given":"Simon D.","family":"Harding","sequence":"first","affiliation":[{"name":"Deanery of Biomedical Sciences University of Edinburgh Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Faccenda","sequence":"additional","affiliation":[{"name":"Deanery of Biomedical Sciences University of Edinburgh Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Southan","sequence":"additional","affiliation":[{"name":"Deanery of Biomedical Sciences University of Edinburgh Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam J.","family":"Pawson","sequence":"additional","affiliation":[{"name":"Deanery of Biomedical Sciences University of Edinburgh Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Maffia","sequence":"additional","affiliation":[{"name":"Centre for Immunobiology Institute of Infection, Immunity and Inflammation College of Medical, Veterinary and Life Sciences University of Glasgow Glasgow UK"},{"name":"Institute of Cardiovascular and Medical Sciences College of Medical, Veterinary and Life Sciences University of Glasgow Glasgow UK"},{"name":"Department of Pharmacy University of Naples Federico II Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen P. 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