{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:02:19Z","timestamp":1781737339026,"version":"3.54.5"},"reference-count":85,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800031"],"award-info":[{"award-number":["81800031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","award":["2020JJ4521"],"award-info":[{"award-number":["2020JJ4521"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2016A030310182"],"award-info":[{"award-number":["2016A030310182"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2018A030313648"],"award-info":[{"award-number":["2018A030313648"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Group 2 innate lymphoid cells (ILC2s) are an important component of the innate immune system that execute important effector functions at barrier surfaces, such as lung and skin. Like T helper type 2 cells, ILC2s are able to release high amounts of type 2 cytokines that are essential in inducing allergic inflammation and eliminating helminth infections. The past few years have contributed to our better understanding of the interactions between ILC2s and other cells of the immune system via soluble factors or in a cell\u2013cell contact manner. Myeloid cells, including mononuclear leukocytes and polymorphonuclear leukocytes, are excellent sensors of tissue damage and infection and can influence ILC2 responses in the process of allergic inflammation. In this review, we summarize recent insights on how myeloid cell subsets regulate ILC2 activation with focus on soluble factors in the context of allergic inflammation.<\/jats:p>","DOI":"10.1111\/imm.13232","type":"journal-article","created":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T19:59:07Z","timestamp":1593633547000},"page":"18-24","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Role of myeloid cells in the regulation of group 2 innate lymphoid cell\u2010mediated allergic inflammation"],"prefix":"10.1111","volume":"161","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1498-5520","authenticated-orcid":false,"given":"Aihua","family":"Lei","sequence":"first","affiliation":[{"name":"Institute of Pathogenic Biology Hengyang Medical College Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study University of South China Hengyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Immunology School of Basic Medical Sciences Southern Medical University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Yang","sequence":"additional","affiliation":[{"name":"Chronic Disease Laboratory Institutes for Life Sciences and School of Medicine South China University of Technology Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofang","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Pathogenic Biology Hengyang Medical College Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study University of South China Hengyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranhui","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Pathogenic Biology Hengyang Medical College Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study University of South China Hengyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.03.018"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201403-097AW"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2017.08.290"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20172359"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3489"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12706"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2131"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21041350"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-019-03228-9"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02694"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01422"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00191"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00423"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.42"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3341"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2017.99"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3070"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157571"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129122"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2045"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1400580"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1502218"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02375"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20121964"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.2741\/3279"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2011.3.3.199"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20040035"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.130"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.11.029"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3308"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3309"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.04.043"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.03.008"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-019-0333-y"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20042311"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3294"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3399"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2017.12.004"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b19-00095"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aax7006"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.03.007"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02051"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-020-0298-2"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002365"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2506"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.8.5791"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00678-2"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI89717"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.04.035"},{"key":"e_1_2_8_51_1","first-page":"4171","article-title":"Passive transfer of lipopolysaccharide\u2010derived myeloid\u2010derived suppressor cells inhibits asthma\u2010related airway inflammation","volume":"19","author":"Fan HZ","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13040"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1101746"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011944"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0226701"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.09.049"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2017.04.017"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.06.021"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14017"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.10.056"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2584"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.10.042"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3427"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.08.011"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2018.03.007"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-016-0321-z"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.04.013"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13197"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2019.04.016"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1401307"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.03.048"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004812"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601569"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10329"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-007-6527-y"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12526"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00329-06"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.2.1021"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1304046110"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.12.885"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13997"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3444"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3078"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601421"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02023-z"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-019-0423-0"}],"container-title":["Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fimm.13232","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imm.13232","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/imm.13232","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imm.13232","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T14:57:41Z","timestamp":1693925861000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imm.13232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/imm.13232"],"URL":"https:\/\/doi.org\/10.1111\/imm.13232","archive":["Portico"],"relation":{},"ISSN":["0019-2805","1365-2567"],"issn-type":[{"value":"0019-2805","type":"print"},{"value":"1365-2567","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,3]]},"assertion":[{"value":"2020-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}