{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:10:58Z","timestamp":1791947458405,"version":"4.3.4"},"reference-count":236,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T00:00:00Z","timestamp":1655856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI142742"],"award-info":[{"award-number":["AI142742"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI144462"],"award-info":[{"award-number":["AI144462"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunological Reviews"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Immunological memory is the basis of protective immunity provided by vaccines and previous infections. Immunological memory can develop from multiple branches of the adaptive immune system, including CD4 T cells, CD8 T cells, B cells, and long\u2010lasting antibody responses. Extraordinary progress has been made in understanding memory to SARS\u2010CoV\u20102 infection and COVID\u201019 vaccines, addressing development; quantitative and qualitative features of different cellular and anatomical compartments; and durability of each cellular component and antibodies. Given the sophistication of the measurements; the size of the human studies; the use of longitudinal samples and cross\u2010sectional studies; and head\u2010to\u2010head comparisons between infection and vaccines or between multiple vaccines, the understanding of immune memory for 1\u2009year to SARS\u2010CoV\u20102 infection and vaccines already supersedes that of any other acute infectious disease. This knowledge may help inform public policies regarding COVID\u201019 and COVID\u201019 vaccines, as well as the scientific development of future vaccines against SARS\u2010CoV\u20102 and other diseases.<\/jats:p>","DOI":"10.1111\/imr.13089","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T01:51:01Z","timestamp":1655949061000},"page":"27-46","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":273,"title":["Immunological memory to\n                    <scp>SARS\u2010CoV<\/scp>\n                    \u20102 infection and\n                    <scp>COVID<\/scp>\n                    \u201019 vaccines"],"prefix":"10.1111","volume":"310","author":[{"given":"Alessandro","family":"Sette","sequence":"first","affiliation":[{"name":"Center for Infectious Disease and Vaccine Research La Jolla Institute for Immunology (LJI)  La Jolla California USA"},{"name":"Division of Infectious Diseases and Global Public Health, Department of Medicine University of California, San Diego (UCSD)  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6484-6262","authenticated-orcid":false,"given":"Shane","family":"Crotty","sequence":"additional","affiliation":[{"name":"Center for Infectious Disease and Vaccine Research La Jolla Institute for Immunology (LJI)  La Jolla California USA"},{"name":"Division of Infectious Diseases and Global Public Health, Department of Medicine University of California, San Diego (UCSD)  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,22]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Immunological Memory","author":"Schoenberger SP","year":"2010"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abj2258"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf4063"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2021.100354"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2034545"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100861"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(21)00675\u20109"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab495"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010021\u201001548\u20107"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2200133"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7104e1"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00462-7"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.01.11.22269045"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2119658"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2034577"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2113017"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(21)02183\u20108"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2114228"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010022\u201001721\u20106"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.01.011"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010022\u201001715\u20104"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.01.007"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010021\u201000578\u2010z"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.13091"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3031"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.09.038"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010021\u201001084\u2010z"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.08.017"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010020\u20100782\u20106"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2020.100092"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010020\u201003041\u20106"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2022.100520"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2022.100562"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2020.101418"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0186998"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature24633"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010020\u20102550\u2010z"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.05.015"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010021\u201000902\u20108"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.11.029"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abf7517"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.05.010"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003653\u20106"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003841\u20104"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201022811\u2010y"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.12.002"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.04.009"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci140491"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abe4782"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2021.100204"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2021.100355"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci149335"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab143"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.05.010"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2021.100312"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.2100727"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.7326\/m21\u20101991"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.7326\/m20\u20100504"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-01780-9"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010020\u20100869\u20105"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.03.031"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abl9105"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abk1741"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010021\u201001095\u2010w"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010021\u201001123\u20109"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010021\u201001089\u20108"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201024938\u20104"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.09.016"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.04.003"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202149556"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.155145"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.793197"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010022\u201001724\u20103"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abm8108"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abk0894"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abj9853"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.01.015"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abl5344"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.03.18.484953"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abm0829"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.01.029"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiab593"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2022483"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2024671"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2034201"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2108829"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201004460\u20103"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010021\u201001464\u2010w"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004120\u2010y"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16818"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2115596"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2116414"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(21)01694\u20109"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(21)02717\u20103"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medj.2021.12.004"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010022\u201001700\u2010x"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201004465\u2010y"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abj1750"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.10.011"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.12.13.472159"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010022\u201001184\u20104"},{"key":"e_1_2_12_103_1","volume-title":"Janeway\u2019s Immunobiology","author":"Weaver C","year":"2016"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3803"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.04.011"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2612"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1505956112"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00019"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abo1303"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20202515"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010022\u201001175\u20105"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.02.063"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.8.5490"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2006.05.002"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.03.018"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.10.001"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.2139\/ssrn.3813278"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.03.23.21253885"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs\u20101317569\/v1"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010020\u20100995\u20100"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.08.001"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.06.001"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep26494"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.08.031"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a032102"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010020\u201000808\u2010x"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.110071"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci140965"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2021.1999777"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20202617"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010021\u201000631\u2010x"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abf3698"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2022.01.017"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010020\u20102598\u20109"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abd2071"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010020\u20100389\u2010z"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd3871"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010020\u201001143\u20102"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.11.004"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.2001438"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0901607"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.00089\u201020"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.11.016"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010020\u201000460\u20104"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abh1823"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.2100990"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci143380"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.10.023"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2021.115338"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiab176"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004186\u20108"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201027674\u2010x"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.01.027"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.12.026"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010020\u201001194\u20105"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(20)31604\u20104"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.11.14.21266294"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg9175"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.10.4969"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07231"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1118979109"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20110740"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003696\u20109"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.103743"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.01.050"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abg6916"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.08.025"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.01.018"},{"key":"e_1_2_12_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.09.037"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1921388117"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.04.036"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590\u2010018\u20100260\u20106"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019002782"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004060\u20107"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2017.05.007"},{"key":"e_1_2_12_176_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12512"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.10.085"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.04.012"},{"key":"e_1_2_12_179_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.12.20.473537"},{"key":"e_1_2_12_180_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201004527\u20101"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003738\u20102"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.09.011"},{"key":"e_1_2_12_183_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2026116"},{"key":"e_1_2_12_184_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd7728"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.7326\/m21\u20103272"},{"key":"e_1_2_12_186_1","article-title":"Immunity to the coronavirus may last years, new data hint","author":"Mandavilli A.","year":"2020","journal-title":"The New York Times"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201024230\u20105"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2021.103561"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiac034"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003647\u20104"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abe5511"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564\u2010021\u201001051\u20102"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201026479\u20102"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2004.02.008"},{"key":"e_1_2_12_195_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa066092"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abh2644"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010020\u20101083\u20101"},{"key":"e_1_2_12_198_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.751705"},{"key":"e_1_2_12_199_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.15125"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10010064"},{"key":"e_1_2_12_201_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2103916"},{"key":"e_1_2_12_202_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abj4176"},{"key":"e_1_2_12_203_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2119912"},{"key":"e_1_2_12_204_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010021\u201001527\u2010y"},{"key":"e_1_2_12_205_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2113468"},{"key":"e_1_2_12_206_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.01.21.476344"},{"key":"e_1_2_12_207_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.02.15.22270948"},{"key":"e_1_2_12_208_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7038e1"},{"key":"e_1_2_12_209_1","unstructured":"MarksP.FDA Ad26.COV2.S COVID\u201019 vaccine emergency use authorization amendment review memorandum.2021.https:\/\/www.fda.gov\/media\/153439\/download. Accessed December 1 2021."},{"key":"e_1_2_12_210_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc2103740"},{"key":"e_1_2_12_211_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2026920"},{"key":"e_1_2_12_212_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.08.01.21261297"},{"key":"e_1_2_12_213_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.10.18.21265113"},{"key":"e_1_2_12_214_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abj0299"},{"key":"e_1_2_12_215_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg9857"},{"key":"e_1_2_12_216_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003207\u2010w"},{"key":"e_1_2_12_217_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.02.14.480394"},{"key":"e_1_2_12_218_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004117\u20107"},{"key":"e_1_2_12_219_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004389\u2010z"},{"key":"e_1_2_12_220_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.3341"},{"key":"e_1_2_12_221_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.02.10.22270789"},{"key":"e_1_2_12_222_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.02.09.22270692"},{"key":"e_1_2_12_223_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.01.13.22269243"},{"key":"e_1_2_12_224_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abn8590"},{"key":"e_1_2_12_225_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01441"},{"key":"e_1_2_12_226_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010021\u201001507\u20102"},{"key":"e_1_2_12_227_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000013108"},{"key":"e_1_2_12_228_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abn8014"},{"key":"e_1_2_12_229_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201004387\u20101"},{"key":"e_1_2_12_230_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abi6950"},{"key":"e_1_2_12_231_1","doi-asserted-by":"publisher","DOI":"10.1101\/2022.01.12.22269192"},{"key":"e_1_2_12_232_1","article-title":"Your immune system evolves to fight coronavirus variants \u2013 scientific American","author":"Brouillette M","year":"2021","journal-title":"Scientific American."},{"key":"e_1_2_12_233_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.12.28.474333"},{"key":"e_1_2_12_234_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010021\u201000657\u20101"},{"key":"e_1_2_12_235_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.10.31.466651"},{"key":"e_1_2_12_236_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.09.16.21263686"},{"key":"e_1_2_12_237_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.07.008"}],"container-title":["Immunological Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imr.13089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/imr.13089","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imr.13089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T19:06:21Z","timestamp":1692731181000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imr.13089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,22]]},"references-count":236,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/imr.13089"],"URL":"https:\/\/doi.org\/10.1111\/imr.13089","archive":["Portico"],"relation":{},"ISSN":["0105-2896","1600-065X"],"issn-type":[{"value":"0105-2896","type":"print"},{"value":"1600-065X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,22]]},"assertion":[{"value":"2021-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}