{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T19:25:34Z","timestamp":1783452334526,"version":"3.55.0"},"reference-count":167,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunological Reviews"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Glioma, the predominant form of central nervous system (CNS) malignancies, presents a significant challenge due to its high prevalence and low 5\u2010year survival rate. The efficacy of current treatment methods is limited by the presence of the blood\u2013brain barrier, the immunosuppressive microenvironment, and other factors. Immunotherapy has emerged as a promising approach, as it can overcome the blood\u2013brain barrier. A tumor's immune privilege, which is induced by an immunosuppressive environment, constricts immunotherapy's clinical impact in glioma. Pyroptosis, a programmed cell death mechanism facilitated by gasdermins, plays a significant role in the management of glioma. Its ability to initiate and regulate tumor occurrence, progression, and metastasis is well\u2010established. However, it is crucial to note that uncontrolled or excessive cell death can result in tissue damage, acute inflammation, and cytokine release syndrome, thereby potentially promoting tumor advancement or recurrence. This paper aims to elucidate the molecular pathways involved in pyroptosis and subsequently discuss its induction in cancer therapy. In addition, the current treatment methods of glioma and the use of pyroptosis in these treatments are introduced. It is hoped to provide more ideas for the treatment of glioma.<\/jats:p>","DOI":"10.1111\/imr.13294","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T10:13:36Z","timestamp":1702030416000},"page":"152-168","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Pyroptosis in glioma: Current management and future application"],"prefix":"10.1111","volume":"321","author":[{"given":"Zeshang","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Neurosurgery The First Bethune Hospital of Jilin University  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenjin","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The First Bethune Hospital of Jilin University  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Radiology The First Bethune Hospital of Jilin University  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingmei","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Medical Technology Chengdu University of Traditional Chinese Medicine  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6441-9607","authenticated-orcid":false,"given":"Xinyu","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The First Bethune Hospital of Jilin University  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noac202"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.path.2021.05.003"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.02.002"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.32604\/oncologie.2022.024898"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19102879"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.03.197"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14432"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2014.12.013"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2022.101405"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00091"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.7573\/dic.2019-9-2"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.554313"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-019-0433-y"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-021-09997-9"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.917634"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.03.012"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-019-0619-4"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.603911"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-022-00905-x"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-021-02065-8"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.71086"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00507-5"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2017.05.005"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-021-00154-z"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1708194114"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09397-2"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109595"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-022-01392-3"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20190545"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature15514"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13683"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-00869-6"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.151"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.58"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aas8995"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13449"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0913087107"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707370105"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd0811"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2020.100863"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature02664"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature15541"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1883-8"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231810494"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0228-2"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201545772"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-019-0368-3"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.10.009"},{"issue":"11","key":"e_1_2_12_50_1","first-page":"1276","article-title":"Role of non\u2010canonical pyroptosis in sepsis and other inflammatory diseases","volume":"46","author":"Liang H","year":"2021","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature22393"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abc3465"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2071-9"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-20-0525"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz7548"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-0575-z"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-00582-w"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2079-1"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-2476-2"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-019-01515-1"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.60292"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2020.114023"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1441-4"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10565-020-09514-8"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-019-0222-z"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR05001J"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.02.012"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2021.02.043"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.460"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf7532"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2022.07.1841"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2021.11.023"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-022-02533-9"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443404"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxres\/tfab107"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154596"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1789-5"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154142"},{"key":"e_1_2_12_79_1","article-title":"Osthole induces apoptosis and caspase\u20103\/GSDME\u2010dependent pyroptosis via NQO1\u2010mediated ROS generation in HeLa cells","volume":"2022","author":"Wang J","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154528"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2021.09.003"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-021-00506-9"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-19-0672"},{"issue":"2","key":"e_1_2_12_84_1","first-page":"436","article-title":"Endogenous HMGB1 regulates GSDME\u2010mediated pyroptosis via ROS\/ERK1\/2\/caspase\u20103\/GSDME signaling in neuroblastoma","volume":"13","author":"Fan C\u2010Y","year":"2023","journal-title":"Am J Cancer Res"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2023.03.002"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41963"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.06.028"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201846935"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izab217"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.853204"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113881"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1761-4"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.79945"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.2174\/15680266113139990125"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2022.08.026"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.1c02790"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-41121-z"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2016.5099"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aat2738"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.774807"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154184"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2195-8"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119546"},{"key":"e_1_2_12_104_1","doi-asserted-by":"crossref","unstructured":"ShiK ChenF LiX LiangC WeiL.GS and GPAs relieve radiation\u2010induced apoptosis and pyroptosis in intestinal epithelial cell via Caspase3\/GSDME pathway.Research Square.2023.","DOI":"10.21203\/rs.3.rs-2503686\/v1"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2023.166637"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-023-01255-5"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2023.105534"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-018-0617-2"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-022-03010-2"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-0669-6"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.108717"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb9818"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4326-3"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04488-5"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.17104"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13060904"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-14732-6_11"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-325334"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2019.01.004"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.32604\/oncologie.2022.020993"},{"issue":"3","key":"e_1_2_12_121_1","article-title":"Current FDA\u2010approved therapies for high\u2010grade malignant gliomas","volume":"9","author":"Fisher JP","year":"2021","journal-title":"Biomedicine"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-22-0887"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom12101348"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI149258"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.18718"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-016-0418-0"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.1024"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-2500"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noac099"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.8219"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02347-y"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-021-01191-2"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1838"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.40298"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12010242"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2022.102554"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15041207"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.921051"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.21037\/tcr.2020.02.17"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-021-00752-y"},{"key":"e_1_2_12_141_1","doi-asserted-by":"crossref","unstructured":"PanH WangQ NiuW et\u00a0al.Mel aggravates pyroptosis induced by temozolomide through inhibiting NRF2\u2010are pathway in glioblastoma.Research Square.2020.","DOI":"10.21203\/rs.3.rs-35576\/v1"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.2217\/epi-2017-0022"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-021-02434-5"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-022-05528-8"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S406782"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2023.154511"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.3727\/096504016X14813859905646"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2022.03.089"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-023-01373-4"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23063360"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2016.1187281"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.00942"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6227"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.614419"},{"issue":"13","key":"e_1_2_12_155_1","first-page":"3589","article-title":"Anti\u2010glioma mechanism of pterostilbene by regulating apoptosis and GSDME\u2010mediated pyroptosis pathways: a study based on network pharmacology and experimental research","volume":"48","author":"Chen Z","year":"2023","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202203583"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c01559"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202207604"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-023-01108-1"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1062225"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.17061"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S341774"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.763807"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.1025065"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/6603151"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.818283"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.781538"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-023-01710-6"}],"container-title":["Immunological Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/imr.13294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T09:28:19Z","timestamp":1710235699000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/imr.13294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,8]]},"references-count":167,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/imr.13294"],"URL":"https:\/\/doi.org\/10.1111\/imr.13294","archive":["Portico"],"relation":{},"ISSN":["0105-2896","1600-065X"],"issn-type":[{"value":"0105-2896","type":"print"},{"value":"1600-065X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,8]]},"assertion":[{"value":"2023-12-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}