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It is associated with poor treatment outcomes, which can be further fuelled by frequent exclusion from specialist treatment due to the separation between mental health and drug and alcohol services. Cognitive Behavioural Therapy (CBT) has an extensive evidence base in treating mental health and substance use disorders in isolation, but there is a paucity of evidence regarding its efficacy in treating DD. The current systematic review aimed to explore the use and effectiveness of CBT as a treatment for individuals with DD. Sources were derived in September 2024 from electronic databases including Medline, PsychINFO, Embase and CINAHL; topically relevant meta\u2010analyses were also citation tracked. Twenty\u2010three studies were included in this review from a total of 2364 which were initially retrieved. Study outcomes highlighted that CBT\u2010based interventions provided some level of improvement to mental health or substance use symptoms, although several interventions did not display superiority when compared to typical addiction approaches. Mental health nurses are well suited to deliver CBT\u2010based interventions and could address the current treatment gap experienced by individuals with DD. This could include supporting patients in maintaining and generalising CBT skills that have already been acquired, which would help guarantee accessibility to CBT\u2010based interventions over a longer time period. However, additional support structures would need to be implemented to allow nurses to deliver CBT effectively, such as access to training, supervision, protected time and reflective practice.<\/jats:p>","DOI":"10.1111\/inm.70129","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T13:58:58Z","timestamp":1760795938000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cognitive Behavioural Therapy and Dual Diagnosis: A Systematic Review Exploring Its Effectiveness and Implications for Nursing Practice"],"prefix":"10.1111","volume":"34","author":[{"given":"Dominic","family":"Nessbach","sequence":"first","affiliation":[{"name":"Florence Nightingale Faculty of Nursing, Midwifery &amp; Palliative Care James Clerk Maxwell Building, Kings College London Waterloo Campus  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3286-9846","authenticated-orcid":false,"given":"Alan","family":"Simpson","sequence":"additional","affiliation":[{"name":"Florence Nightingale Faculty of Nursing, Midwifery &amp; Palliative Care James Clerk Maxwell Building, Kings College London Waterloo Campus  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10061307"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/01612840.2020.1806964"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2018.11.032"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c6325"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291714000208"},{"volume-title":"Cognitive Therapy of Substance Abuse","year":"1993","author":"Beck A. 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