{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:03:20Z","timestamp":1787504600790,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,9,28]],"date-time":"2012-09-28T00:00:00Z","timestamp":1348790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Prolonged oral respiration is known to cause postural alterations, which can lead to dental malocclusions. Allergic rhinitis, a common cause of upper airway obstruction in children, must therefore be seen as a possible risk factor in the development of malocclusions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Aim of this study was to investigate the association between allergic rhinitis and malocclusions in primary and early\u2010mixed dentition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A case\u2013control study was carried out involving 275 Italian children aged 5\u20139. The case group and the control group were composed of 125 individuals affected by malocclusions and by 150 healthy patients, respectively. Through a questionnaire, we assessed the presence of professionally diagnosed allergic rhinitis. Data were analysed to identify associations between these variables and the presence of malocclusions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Children with a history of allergic rhinitis had a threefold increased risk to develop one or more dento\u2010skeletal alterations [\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u00a0=\u00a03.16; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      (1.79\u20135.58),\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001]. Statistically significant associations were found between allergic rhinitis and the development of posterior crossbite and increased overjet. No significant association was found for anterior openbite.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Allergic rhinitis is a significant risk factor for the development of malocclusions in general and is associated with the development of posterior crossbite and increased overjet.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ipd.12003","type":"journal-article","created":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T07:33:41Z","timestamp":1348990421000},"page":"274-278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Allergic rhinitis as a possible risk factor for malocclusion: a case\u2013control study in children"],"prefix":"10.1111","volume":"23","author":[{"given":"Valeria","family":"Luzzi","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillo\u2010Facial Sciences Sapienza University of Rome Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Ierardo","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillo\u2010Facial Sciences Sapienza University of Rome Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Viscogliosi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillo\u2010Facial Sciences Sapienza University of Rome Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Fabbrizi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillo\u2010Facial Sciences Sapienza University of Rome Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana","family":"Consoli","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillo\u2010Facial Sciences Sapienza University of Rome Roma 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