{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:26:38Z","timestamp":1777490798055,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Calcium hydroxide indirect pulp treatment (<jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IPT<\/jats:styled-content>) and antibiotic sterilization using a mixture of three antibiotics (3<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ix\u2010<jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content>) of deep caries are similar non\u2010invasive vital pulp treatments. No studies have compared their clinical and radiographic success rates in primary molars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare the clinical and radiographic success rates of <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IPT<\/jats:styled-content> and 3<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ix\u2010<jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> in carious lesions approaching the pulp of mandibular primary molars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Eighty\u2010two mandibular primary molars from 50 children, aged 3\u20138\u00a0years, with carious lesions approaching the pulp, and meeting the inclusion criteria, were randomly assigned for either treatment. After treatment, blinded clinical\/radiographic evaluation was performed at 6\u201311 and 12\u201329\u00a0month recalls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6\u201311\u00a0months, the overall success rates of <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IPT<\/jats:styled-content> and 3<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ix\u2010<jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> were 82% and 81% <jats:italic>(P\u00a0=\u00a00.91),<\/jats:italic> respectively. At 12\u201329\u00a0months, the success rates were 94% and 78% <jats:italic>(P\u00a0=\u00a00.08),<\/jats:italic> respectively. The most frequently observed failure at the 12\u201329\u00a0month recall was internal resorption (one <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IPT<\/jats:styled-content> tooth and three 3<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ix\u2010<jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> teeth).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There was no statistically significant difference in overall success rates between <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IPT<\/jats:styled-content> and 3<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ix\u2010<jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> in treating deep caries approaching the pulp in mandibular primary molars at either 6\u201311\u00a0month or 12\u201329\u00a0month 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