{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T21:37:29Z","timestamp":1793914649447,"version":"4.8.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T00:00:00Z","timestamp":1477872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Individuals with special needs are often affected by oral disorders such as dental caries and periodontal disease. Current data regarding prevalence of these conditions in individuals with autism spectrum disorders (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>) are controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To conduct a systematic review and meta\u2010analysis to verify the prevalence of dental caries and periodontal disease in individuals with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>, especially children and young adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Searches were conducted through <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>\/PubMed, Web of Science, and Scopus databases in December 2015. Studies were included if fulfilled the following eligibility criteria: to evaluate the oral health status of individuals with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>; to be an observational study; and to assess the prevalence of dental caries and\/or periodontal disease. Meta\u2010analyses were conducted considering prevalence of dental caries and periodontal disease in individuals as outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Search strategy identified 928 potentially relevant articles and seven of them were included in this review. All included studies reported dental caries prevalence, and the pooled prevalence was 60.6% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 44.0\u201375.1). Moreover, only three studies showed prevalence of periodontal disease, resulting in pooled prevalence of 69.4% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 47.6\u201385.0).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Prevalence of dental caries and periodontal disease in children and young adults with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> can be considered as high, pointing to the need for oral health policies focused on these individuals.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ipd.12274","type":"journal-article","created":{"date-parts":[[2016,10,31]],"date-time":"2016-10-31T06:32:50Z","timestamp":1477895570000},"page":"388-398","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":148,"title":["Oral health status of children and young adults with autism spectrum disorders: systematic review and 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